Does neuroinflammation induce systemic aging?

Research output: Contribution to journalArticle

Abstract

A recent article published in Nature presents intriguing data suggesting that the activation of neuronal nuclear factor-κB (NF-κB) in the mediobasal hypothalamus (MBH) causes systemic aging through reduced secretion of gonadotropin-releasing hormone, an anti-aging hormone. Microglial inflammation in MBH also seems to induce neuronal NF-κB. These results raise the possibility that neuroinflammation orchestrates systemic aging.

Original languageEnglish
Pages (from-to)155-156
Number of pages2
JournalClinical and Experimental Neuroimmunology
Volume4
Issue number2
DOIs
Publication statusPublished - 2013 Aug

Fingerprint

Hypothalamus
Gonadotropin-Releasing Hormone
Hormones
Inflammation

ASJC Scopus subject areas

  • Clinical Neurology
  • Immunology and Microbiology (miscellaneous)
  • Neuroscience (miscellaneous)
  • Immunology

Cite this

Does neuroinflammation induce systemic aging? / Nakahara, Jin.

In: Clinical and Experimental Neuroimmunology, Vol. 4, No. 2, 08.2013, p. 155-156.

Research output: Contribution to journalArticle

@article{85d9fc93d92140c989f70379cd53f808,
title = "Does neuroinflammation induce systemic aging?",
abstract = "A recent article published in Nature presents intriguing data suggesting that the activation of neuronal nuclear factor-κB (NF-κB) in the mediobasal hypothalamus (MBH) causes systemic aging through reduced secretion of gonadotropin-releasing hormone, an anti-aging hormone. Microglial inflammation in MBH also seems to induce neuronal NF-κB. These results raise the possibility that neuroinflammation orchestrates systemic aging.",
author = "Jin Nakahara",
year = "2013",
month = "8",
doi = "10.1111/cen3.12038",
language = "English",
volume = "4",
pages = "155--156",
journal = "Clinical and Experimental Neuroimmunology",
issn = "1759-1961",
publisher = "John Wiley and Sons Ltd",
number = "2",

}

TY - JOUR

T1 - Does neuroinflammation induce systemic aging?

AU - Nakahara, Jin

PY - 2013/8

Y1 - 2013/8

N2 - A recent article published in Nature presents intriguing data suggesting that the activation of neuronal nuclear factor-κB (NF-κB) in the mediobasal hypothalamus (MBH) causes systemic aging through reduced secretion of gonadotropin-releasing hormone, an anti-aging hormone. Microglial inflammation in MBH also seems to induce neuronal NF-κB. These results raise the possibility that neuroinflammation orchestrates systemic aging.

AB - A recent article published in Nature presents intriguing data suggesting that the activation of neuronal nuclear factor-κB (NF-κB) in the mediobasal hypothalamus (MBH) causes systemic aging through reduced secretion of gonadotropin-releasing hormone, an anti-aging hormone. Microglial inflammation in MBH also seems to induce neuronal NF-κB. These results raise the possibility that neuroinflammation orchestrates systemic aging.

UR - http://www.scopus.com/inward/record.url?scp=84883388410&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84883388410&partnerID=8YFLogxK

U2 - 10.1111/cen3.12038

DO - 10.1111/cen3.12038

M3 - Article

AN - SCOPUS:84883388410

VL - 4

SP - 155

EP - 156

JO - Clinical and Experimental Neuroimmunology

JF - Clinical and Experimental Neuroimmunology

SN - 1759-1961

IS - 2

ER -