Dosimetric variations due to interfraction organ deformation in cervical cancer brachytherapy

Kazuma Kobayashi, Naoya Murakami, Akihisa Wakita, Satoshi Nakamura, Hiroyuki Okamoto, Rei Umezawa, Kana Takahashi, Koji Inaba, Hiroshi Igaki, Yoshinori Ito, Naoyuki Shigematsu, Jun Itami

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

We quantitatively estimated dosimetric variations due to interfraction organ deformation in multi-fractionated high-dose-rate brachytherapy (HDRBT) for cervical cancer using a novel surface-based non-rigid deformable registration. As the number of consecutive HDRBT fractions increased, simple addition of dose-volume histogram parameters significantly overestimated the dose, compared with distribution-based dose addition.

Original languageEnglish
Pages (from-to)555-558
Number of pages4
JournalRadiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Volume117
Issue number3
DOIs
Publication statusPublished - 2015 Dec 1

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Keywords

  • Brachytherapy
  • Cervical cancer
  • Deformable registration
  • Dose evaluation
  • Interfraction variation

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Radiology Nuclear Medicine and imaging

Cite this

Kobayashi, K., Murakami, N., Wakita, A., Nakamura, S., Okamoto, H., Umezawa, R., Takahashi, K., Inaba, K., Igaki, H., Ito, Y., Shigematsu, N., & Itami, J. (2015). Dosimetric variations due to interfraction organ deformation in cervical cancer brachytherapy. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 117(3), 555-558. https://doi.org/10.1016/j.radonc.2015.08.017