Dosimetric variations due to interfraction organ deformation in cervical cancer brachytherapy

Kazuma Kobayashi; Naoya Murakami; Akihisa Wakita; Satoshi Nakamura; Hiroyuki Okamoto; Rei Umezawa; Kana Takahashi; Koji Inaba; Hiroshi Igaki; Yoshinori Ito; Naoyuki Shigematsu; Jun Itami

doi:10.1016/j.radonc.2015.08.017

Dosimetric variations due to interfraction organ deformation in cervical cancer brachytherapy

Kazuma Kobayashi, Naoya Murakami, Akihisa Wakita, Satoshi Nakamura, Hiroyuki Okamoto, Rei Umezawa, Kana Takahashi, Koji Inaba, Hiroshi Igaki, Yoshinori Ito, Naoyuki Shigematsu, Jun Itami

Department of Radiology (Radiation Oncology)

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

We quantitatively estimated dosimetric variations due to interfraction organ deformation in multi-fractionated high-dose-rate brachytherapy (HDRBT) for cervical cancer using a novel surface-based non-rigid deformable registration. As the number of consecutive HDRBT fractions increased, simple addition of dose–volume histogram parameters significantly overestimated the dose, compared with distribution-based dose addition.

Original language	English
Pages (from-to)	555-558
Number of pages	4
Journal	Radiotherapy and Oncology
Volume	117
Issue number	3
DOIs	https://doi.org/10.1016/j.radonc.2015.08.017
Publication status	Published - 2015 Dec

Keywords

Brachytherapy
Cervical cancer
Deformable registration
Dose evaluation
Interfraction variation

ASJC Scopus subject areas

Hematology
Oncology
Radiology Nuclear Medicine and imaging

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Dosimetric variations due to interfraction organ deformation in cervical cancer brachytherapy. / Kobayashi, Kazuma; Murakami, Naoya; Wakita, Akihisa; Nakamura, Satoshi; Okamoto, Hiroyuki; Umezawa, Rei; Takahashi, Kana; Inaba, Koji; Igaki, Hiroshi; Ito, Yoshinori; Shigematsu, Naoyuki; Itami, Jun.

In: Radiotherapy and Oncology, Vol. 117, No. 3, 12.2015, p. 555-558.

Research output: Contribution to journal › Article › peer-review

Kobayashi, Kazuma ; Murakami, Naoya ; Wakita, Akihisa ; Nakamura, Satoshi ; Okamoto, Hiroyuki ; Umezawa, Rei ; Takahashi, Kana ; Inaba, Koji ; Igaki, Hiroshi ; Ito, Yoshinori ; Shigematsu, Naoyuki ; Itami, Jun. / Dosimetric variations due to interfraction organ deformation in cervical cancer brachytherapy. In: Radiotherapy and Oncology. 2015 ; Vol. 117, No. 3. pp. 555-558.

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abstract = "We quantitatively estimated dosimetric variations due to interfraction organ deformation in multi-fractionated high-dose-rate brachytherapy (HDRBT) for cervical cancer using a novel surface-based non-rigid deformable registration. As the number of consecutive HDRBT fractions increased, simple addition of dose–volume histogram parameters significantly overestimated the dose, compared with distribution-based dose addition.",

keywords = "Brachytherapy, Cervical cancer, Deformable registration, Dose evaluation, Interfraction variation",

author = "Kazuma Kobayashi and Naoya Murakami and Akihisa Wakita and Satoshi Nakamura and Hiroyuki Okamoto and Rei Umezawa and Kana Takahashi and Koji Inaba and Hiroshi Igaki and Yoshinori Ito and Naoyuki Shigematsu and Jun Itami",

note = "Funding Information: This work has been financially supported by the Health and Labor Sciences Research Expenses for Commission H26-applied-general-036 and Grant-in-Aid for Young Scientists (B) from the Ministry of Education, Culture, Sports, Science, and Technology of Japan (Grant number 15K19837 ). ",

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AU - Kobayashi, Kazuma

AU - Murakami, Naoya

AU - Wakita, Akihisa

AU - Nakamura, Satoshi

AU - Okamoto, Hiroyuki

AU - Umezawa, Rei

AU - Takahashi, Kana

AU - Inaba, Koji

AU - Igaki, Hiroshi

AU - Ito, Yoshinori

AU - Shigematsu, Naoyuki

AU - Itami, Jun

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PY - 2015/12

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N2 - We quantitatively estimated dosimetric variations due to interfraction organ deformation in multi-fractionated high-dose-rate brachytherapy (HDRBT) for cervical cancer using a novel surface-based non-rigid deformable registration. As the number of consecutive HDRBT fractions increased, simple addition of dose–volume histogram parameters significantly overestimated the dose, compared with distribution-based dose addition.

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KW - Brachytherapy

KW - Cervical cancer

KW - Deformable registration

KW - Dose evaluation

KW - Interfraction variation

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