E-cell project: towards computer modeling of the whole cell

Research output: Contribution to journalConference articlepeer-review


The E-CELL System (http://www.e-cell.org) is a genetic software package developed, to model not only metabolic pathways but also other higher-order cellular processes such as protein synthesis and signal transduction. Using the system, we have successfully constructed a virtual cell with 127 genes sufficient for 'self-support'. The gene set was selected from the genome of Mycoplasma genitalium, and the metabolisms include transcription, translation, membrane transport, the glycolysis pathway for energy production, and the phospholipid biosynthesis pathway or membrane structure.

Original languageEnglish
Pages (from-to)S-30
JournalAnnals of Biomedical Engineering
Issue numberSUPPL. 1
Publication statusPublished - 2000 Dec 1
Event2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA
Duration: 2000 Oct 122000 Oct 14

ASJC Scopus subject areas

  • Biomedical Engineering


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