Early recovery from acquired child aphasia and changes of cerebral blood flow

Tomoyuki Kojima, Masaru Mimura, Kenichi Auchi, Masahiro Kato

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Research into acquired child aphasia can provide useful evidence about the neural mechanisms involved in recovery from aphasia because the functional plasticity of the brain is greater in children than in adults. To investigate the neural correlates underlying functional recovery from acquired child aphasia, we followed a 9-year-old boy with aphasia for 2-16 months after traumatic head injury. The patient's language ability was assessed four times by the Standard Language Test of Aphasia (SLTA). Regional cerebral blood flow (rCBF) was also measured four times with 99mTc-ECD and a fully automated quantitative image analysis system. The patient showed substantial improvement of language during this period. Although overall rCBF fluctuated throughout the 1st-4th measurements, there was a significant relative dominance of rCBF in the left cerebral hemisphere compared with the right hemisphere throughout the four measurements, especially in the paracentral and temporo-parietal regions. These findings may suggest that the left cerebral hemisphere rather than the right hemisphere plays a major role in the early recovery from child aphasia.

Original languageEnglish
Pages (from-to)451-464
Number of pages14
JournalJournal of Neurolinguistics
Volume22
Issue number5
DOIs
Publication statusPublished - 2009 Sep
Externally publishedYes

Fingerprint

Cerebrovascular Circulation
Aphasia
speech disorder
Regional Blood Flow
Cerebrum
Language
Language Tests
standard language
Parietal Lobe
Aptitude
systems analysis
language
Craniocerebral Trauma
Cerebral Blood Flow
Recovery
brain
Brain
ability

Keywords

  • Cerebral blood flow
  • Child aphasia
  • Recovery
  • Standard Language Test of Aphasia

ASJC Scopus subject areas

  • Linguistics and Language
  • Cognitive Neuroscience
  • Experimental and Cognitive Psychology

Cite this

Early recovery from acquired child aphasia and changes of cerebral blood flow. / Kojima, Tomoyuki; Mimura, Masaru; Auchi, Kenichi; Kato, Masahiro.

In: Journal of Neurolinguistics, Vol. 22, No. 5, 09.2009, p. 451-464.

Research output: Contribution to journalArticle

Kojima, Tomoyuki ; Mimura, Masaru ; Auchi, Kenichi ; Kato, Masahiro. / Early recovery from acquired child aphasia and changes of cerebral blood flow. In: Journal of Neurolinguistics. 2009 ; Vol. 22, No. 5. pp. 451-464.
@article{0a4e0596fb0147d7a68789eeb0bed94d,
title = "Early recovery from acquired child aphasia and changes of cerebral blood flow",
abstract = "Research into acquired child aphasia can provide useful evidence about the neural mechanisms involved in recovery from aphasia because the functional plasticity of the brain is greater in children than in adults. To investigate the neural correlates underlying functional recovery from acquired child aphasia, we followed a 9-year-old boy with aphasia for 2-16 months after traumatic head injury. The patient's language ability was assessed four times by the Standard Language Test of Aphasia (SLTA). Regional cerebral blood flow (rCBF) was also measured four times with 99mTc-ECD and a fully automated quantitative image analysis system. The patient showed substantial improvement of language during this period. Although overall rCBF fluctuated throughout the 1st-4th measurements, there was a significant relative dominance of rCBF in the left cerebral hemisphere compared with the right hemisphere throughout the four measurements, especially in the paracentral and temporo-parietal regions. These findings may suggest that the left cerebral hemisphere rather than the right hemisphere plays a major role in the early recovery from child aphasia.",
keywords = "Cerebral blood flow, Child aphasia, Recovery, Standard Language Test of Aphasia",
author = "Tomoyuki Kojima and Masaru Mimura and Kenichi Auchi and Masahiro Kato",
year = "2009",
month = "9",
doi = "10.1016/j.jneuroling.2009.03.005",
language = "English",
volume = "22",
pages = "451--464",
journal = "Journal of Neurolinguistics",
issn = "0911-6044",
publisher = "Elsevier BV",
number = "5",

}

TY - JOUR

T1 - Early recovery from acquired child aphasia and changes of cerebral blood flow

AU - Kojima, Tomoyuki

AU - Mimura, Masaru

AU - Auchi, Kenichi

AU - Kato, Masahiro

PY - 2009/9

Y1 - 2009/9

N2 - Research into acquired child aphasia can provide useful evidence about the neural mechanisms involved in recovery from aphasia because the functional plasticity of the brain is greater in children than in adults. To investigate the neural correlates underlying functional recovery from acquired child aphasia, we followed a 9-year-old boy with aphasia for 2-16 months after traumatic head injury. The patient's language ability was assessed four times by the Standard Language Test of Aphasia (SLTA). Regional cerebral blood flow (rCBF) was also measured four times with 99mTc-ECD and a fully automated quantitative image analysis system. The patient showed substantial improvement of language during this period. Although overall rCBF fluctuated throughout the 1st-4th measurements, there was a significant relative dominance of rCBF in the left cerebral hemisphere compared with the right hemisphere throughout the four measurements, especially in the paracentral and temporo-parietal regions. These findings may suggest that the left cerebral hemisphere rather than the right hemisphere plays a major role in the early recovery from child aphasia.

AB - Research into acquired child aphasia can provide useful evidence about the neural mechanisms involved in recovery from aphasia because the functional plasticity of the brain is greater in children than in adults. To investigate the neural correlates underlying functional recovery from acquired child aphasia, we followed a 9-year-old boy with aphasia for 2-16 months after traumatic head injury. The patient's language ability was assessed four times by the Standard Language Test of Aphasia (SLTA). Regional cerebral blood flow (rCBF) was also measured four times with 99mTc-ECD and a fully automated quantitative image analysis system. The patient showed substantial improvement of language during this period. Although overall rCBF fluctuated throughout the 1st-4th measurements, there was a significant relative dominance of rCBF in the left cerebral hemisphere compared with the right hemisphere throughout the four measurements, especially in the paracentral and temporo-parietal regions. These findings may suggest that the left cerebral hemisphere rather than the right hemisphere plays a major role in the early recovery from child aphasia.

KW - Cerebral blood flow

KW - Child aphasia

KW - Recovery

KW - Standard Language Test of Aphasia

UR - http://www.scopus.com/inward/record.url?scp=67649644726&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67649644726&partnerID=8YFLogxK

U2 - 10.1016/j.jneuroling.2009.03.005

DO - 10.1016/j.jneuroling.2009.03.005

M3 - Article

AN - SCOPUS:67649644726

VL - 22

SP - 451

EP - 464

JO - Journal of Neurolinguistics

JF - Journal of Neurolinguistics

SN - 0911-6044

IS - 5

ER -