Effect of daily glucose fluctuation on coronary plaque vulnerability in patients pre-treated with lipid-lowering therapy: A prospective observational study

Masaru Kuroda, Toshiro Shinke, Kazuhiko Sakaguchi, Hiromasa Otake, Tomofumi Takaya, Yushi Hirota, Daisuke Sugiyama, Masayuki Nakagawa, Hirotoshi Hariki, Takumi Inoue, Tsuyoshi Osue, Yu Taniguchi, Masamichi Iwasaki, Ryo Nishio, Hiroto Kinutani, Akihide Konishi, Noritoshi Hiranuma, Hachidai Takahashi, Daisuke Terashita, Ken Ichi Hirata

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Objectives This study sought to investigate the effect of daily glucose fluctuation on coronary plaque properties in patients with coronary artery disease (CAD) pre-treated with lipid-lowering therapy. Background There is growing evidence that glucose fluctuation, as a residual risk apart from dyslipidemia, is an important factor contributing to the development of CAD. Methods This prospective study enrolled 70 consecutive CAD patients who were referred for percutaneous coronary intervention and whose low-density lipoprotein cholesterol level was

Original languageEnglish
Pages (from-to)800-811
Number of pages12
JournalJACC: Cardiovascular Interventions
Volume8
Issue number6
DOIs
Publication statusPublished - 2015 May 1

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Observational Studies
Coronary Artery Disease
Prospective Studies
Lipids
Glucose
Percutaneous Coronary Intervention
Dyslipidemias
LDL Cholesterol
Therapeutics

Keywords

  • continuous glucose monitoring
  • glucose fluctuation
  • mean amplitude of glycemic excursion
  • thin-cap fibroatheroma
  • virtual histology intravascular ultrasound

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Effect of daily glucose fluctuation on coronary plaque vulnerability in patients pre-treated with lipid-lowering therapy : A prospective observational study. / Kuroda, Masaru; Shinke, Toshiro; Sakaguchi, Kazuhiko; Otake, Hiromasa; Takaya, Tomofumi; Hirota, Yushi; Sugiyama, Daisuke; Nakagawa, Masayuki; Hariki, Hirotoshi; Inoue, Takumi; Osue, Tsuyoshi; Taniguchi, Yu; Iwasaki, Masamichi; Nishio, Ryo; Kinutani, Hiroto; Konishi, Akihide; Hiranuma, Noritoshi; Takahashi, Hachidai; Terashita, Daisuke; Hirata, Ken Ichi.

In: JACC: Cardiovascular Interventions, Vol. 8, No. 6, 01.05.2015, p. 800-811.

Research output: Contribution to journalArticle

Kuroda, M, Shinke, T, Sakaguchi, K, Otake, H, Takaya, T, Hirota, Y, Sugiyama, D, Nakagawa, M, Hariki, H, Inoue, T, Osue, T, Taniguchi, Y, Iwasaki, M, Nishio, R, Kinutani, H, Konishi, A, Hiranuma, N, Takahashi, H, Terashita, D & Hirata, KI 2015, 'Effect of daily glucose fluctuation on coronary plaque vulnerability in patients pre-treated with lipid-lowering therapy: A prospective observational study', JACC: Cardiovascular Interventions, vol. 8, no. 6, pp. 800-811. https://doi.org/10.1016/j.jcin.2014.11.025
Kuroda, Masaru ; Shinke, Toshiro ; Sakaguchi, Kazuhiko ; Otake, Hiromasa ; Takaya, Tomofumi ; Hirota, Yushi ; Sugiyama, Daisuke ; Nakagawa, Masayuki ; Hariki, Hirotoshi ; Inoue, Takumi ; Osue, Tsuyoshi ; Taniguchi, Yu ; Iwasaki, Masamichi ; Nishio, Ryo ; Kinutani, Hiroto ; Konishi, Akihide ; Hiranuma, Noritoshi ; Takahashi, Hachidai ; Terashita, Daisuke ; Hirata, Ken Ichi. / Effect of daily glucose fluctuation on coronary plaque vulnerability in patients pre-treated with lipid-lowering therapy : A prospective observational study. In: JACC: Cardiovascular Interventions. 2015 ; Vol. 8, No. 6. pp. 800-811.
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