Effect of insulin therapy on body fat distribution in NIDDM patients with secondary sulfonylurea failure: A preliminary report

I. Takei, S. Takayama, A. Yamauchi, S. Nakamoto, Y. Kitamura, Fuminori Katsukawa, H. Yamazaki, T. Saruta, S. Inoue

Research output: Contribution to journalArticle

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Abstract

Objective: To clarify the influence of insulin therapy on body weight and fat distribution, we compared these parameters in five non-insulin dependent diabetes mellitus (NIDDM) patients, with secondary sulfonylurea failure, before and after insulin therapy. Body weight increased significantly after instituting insulin treatment. However, the visceral to subcutaneous fat (V/S) ratio decreased significantly due to a marked increase in S-fat without a change in V-fat. Insulin therapy necessitated by sulfonylurea failure does not appear to accelerate the atherogenic process in NIDDM patients as there is no increase in visceral fat.

Original languageEnglish
Pages (from-to)153-154
Number of pages2
JournalEuropean Journal of Clinical Nutrition
Volume52
Issue number2
Publication statusPublished - 1998 Feb

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Body Fat Distribution
sulfonylureas
body fat distribution
noninsulin-dependent diabetes mellitus
Type 2 Diabetes Mellitus
Insulin
visceral fat
body weight
Fats
Body Weight
subcutaneous fat
lipids
body fat
Intra-Abdominal Fat
Subcutaneous Fat
insulin
Therapeutics
insulin replacement therapy

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Effect of insulin therapy on body fat distribution in NIDDM patients with secondary sulfonylurea failure : A preliminary report. / Takei, I.; Takayama, S.; Yamauchi, A.; Nakamoto, S.; Kitamura, Y.; Katsukawa, Fuminori; Yamazaki, H.; Saruta, T.; Inoue, S.

In: European Journal of Clinical Nutrition, Vol. 52, No. 2, 02.1998, p. 153-154.

Research output: Contribution to journalArticle

Takei, I, Takayama, S, Yamauchi, A, Nakamoto, S, Kitamura, Y, Katsukawa, F, Yamazaki, H, Saruta, T & Inoue, S 1998, 'Effect of insulin therapy on body fat distribution in NIDDM patients with secondary sulfonylurea failure: A preliminary report', European Journal of Clinical Nutrition, vol. 52, no. 2, pp. 153-154.
Takei, I. ; Takayama, S. ; Yamauchi, A. ; Nakamoto, S. ; Kitamura, Y. ; Katsukawa, Fuminori ; Yamazaki, H. ; Saruta, T. ; Inoue, S. / Effect of insulin therapy on body fat distribution in NIDDM patients with secondary sulfonylurea failure : A preliminary report. In: European Journal of Clinical Nutrition. 1998 ; Vol. 52, No. 2. pp. 153-154.
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