Effect of insulin therapy on body fat distribution in NIDDM patients with secondary sulfonylurea failure: A preliminary report

I. Takei, S. Takayama, A. Yamauchi, S. Nakamoto, Y. Kitamura, F. Katsukawa, H. Yamazaki, T. Saruta, S. Inoue

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Objective: To clarify the influence of insulin therapy on body weight and fat distribution, we compared these parameters in five non-insulin dependent diabetes mellitus (NIDDM) patients, with secondary sulfonylurea failure, before and after insulin therapy. Body weight increased significantly after instituting insulin treatment. However, the visceral to subcutaneous fat (V/S) ratio decreased significantly due to a marked increase in S-fat without a change in V-fat. Insulin therapy necessitated by sulfonylurea failure does not appear to accelerate the atherogenic process in NIDDM patients as there is no increase in visceral fat.

Original languageEnglish
Pages (from-to)153-154
Number of pages2
JournalEuropean Journal of Clinical Nutrition
Volume52
Issue number2
DOIs
Publication statusPublished - 1998 Feb

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Fingerprint Dive into the research topics of 'Effect of insulin therapy on body fat distribution in NIDDM patients with secondary sulfonylurea failure: A preliminary report'. Together they form a unique fingerprint.

  • Cite this