Abstract
Thirty-six patients with aplastic anemia and three with aplastic anemia-PNH syndrome in eight institutes were studied for the presence of peripheral blood mononuclear cells having a suppressive effect on granulocyte-macrophage (G-M) and erythroid colony formation using a uniform protocol. In 11 cases of 29 (38%) and 9 cases of 29 (31%), the presence of mononuclear cells with a suppressive effect on G-M and erythroid colony formation, respectively, was demonstrated. However, the presence of mononuclear cells suppressive both to G-M and erythroid colony formation was demonstrated only in 3 of 19 cases (16%).
| Original language | English |
|---|---|
| Pages (from-to) | 937-943 |
| Number of pages | 7 |
| Journal | Blood |
| Volume | 55 |
| Issue number | 6 |
| Publication status | Published - 1980 Aug 18 |
ASJC Scopus subject areas
- Biochemistry
- Immunology
- Hematology
- Cell Biology
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Takaku, F., Suda, T., Mizoguchi, H., Miura, Y., Uchino, H., Nagai, K., Kariyone, S., Shibata, A., Akabane, T., Nomura, T., & Maekawa, T. (1980). Effect of peripheral blood mononuclear cells from aplastic anemia patients on the granulocyte-macrophage and erythroid colony formation in samples from normal human bone marrow in vitro - A cooperative work. Blood, 55(6), 937-943.