Effect of repetitive stimulation on lateral spreads and F-waves in hemifacial spasm

Mami Ishikawa, Jun Namiki, Moriichiro Takase, Takayuki Oohira, Akiyoshi Nakamura, Shigeo Toya

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The lateral spread (LS) response, which can be elicited in muscles innervated by other branches of the facial nerve, is electromyographically specific for patients with hemifacial spasm (HFS), occurring about 10 ms after stimulus. The F-wave in facial muscles, which is a late response that antidromicaly propagates to the facial motonucleus and returns orthodromicaly down the same axon, revealed a trend toward enhancement in patients with HFS. The LSs were facilitated by repetitive stimulation during the microvascular decompression (MVD) operation, which has proved to be a successful treatment, and the F-waves were also facilitated by repetitive stimulation on the spasm side more than on the normal side. Greater facilitation of these responses was in direct proportion to higher stimulation rates and greater numbers of stimulations. The repetitive stimulation of the facial nerve may result in activation of the motoneuron pool and in the lowering of the threshold of somatic membranes. These results support the hypothesis that hemifacial spasm is caused by hyperexcitability of the facial motonucleus, which is increased by antidromic repetitive stimulation.

Original languageEnglish
Pages (from-to)99-106
Number of pages8
JournalJournal of the Neurological Sciences
Volume142
Issue number1-2
DOIs
Publication statusPublished - 1996 Oct

Fingerprint

Hemifacial Spasm
Facial Nerve
Microvascular Decompression Surgery
Facial Muscles
Spasm
Motor Neurons
Axons
Muscles
Membranes
Therapeutics

Keywords

  • electrophysiology
  • F-wave
  • hemifacial spasm
  • lateral spread
  • repetitive stimulation

ASJC Scopus subject areas

  • Ageing
  • Clinical Neurology
  • Surgery
  • Developmental Neuroscience
  • Neurology
  • Neuroscience(all)

Cite this

Effect of repetitive stimulation on lateral spreads and F-waves in hemifacial spasm. / Ishikawa, Mami; Namiki, Jun; Takase, Moriichiro; Oohira, Takayuki; Nakamura, Akiyoshi; Toya, Shigeo.

In: Journal of the Neurological Sciences, Vol. 142, No. 1-2, 10.1996, p. 99-106.

Research output: Contribution to journalArticle

Ishikawa, Mami ; Namiki, Jun ; Takase, Moriichiro ; Oohira, Takayuki ; Nakamura, Akiyoshi ; Toya, Shigeo. / Effect of repetitive stimulation on lateral spreads and F-waves in hemifacial spasm. In: Journal of the Neurological Sciences. 1996 ; Vol. 142, No. 1-2. pp. 99-106.
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