Effect of Superficial Tissue on Spatial Sensitivity Profile of Optical Brain Activity Measurement Evaluated by Direct Hybrid Monte Carlo-Diffusion Method

Toshiyuki Hayashi, Yoshihiko Kashio, Eiji Okada

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The light propagation in the brain is highly affected by the superficial tissues such as skin, skull and cerebrospinal fluid (CSF). The development of an adequate model to calculate light propagation in the head is very important for optical brain activity measurement. We developed a novel approach, the direct hybrid Monte Carlo-diffusion method (DHMDM), which can calculate light propagation in the three-dimensional head models including low scattering regions in which the light propagation does not obey either the diffusion approximation or the radiosity theory. The effect of thickness of the superficial tissue upon the spatial sensitivity profiles for optical brain activity measurement is evaluated by the DHMDM. The sensitivity to the brain activity decreases with increasing thickness of the superficial layer whilst the spatial decay of sensitivity on the brain surface depends little upon the thickness of the superficial layer.

Original languageEnglish
Pages (from-to)501-505
Number of pages5
JournalOptical Review
Volume10
Issue number5
Publication statusPublished - 2003 Sep

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brain
sensitivity
profiles
propagation
cerebrospinal fluid
skull
fluids
decay
approximation
scattering

Keywords

  • Biomedical optics
  • Brain activity
  • Diffusion equation
  • Finite element method
  • Light propagation

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Effect of Superficial Tissue on Spatial Sensitivity Profile of Optical Brain Activity Measurement Evaluated by Direct Hybrid Monte Carlo-Diffusion Method. / Hayashi, Toshiyuki; Kashio, Yoshihiko; Okada, Eiji.

In: Optical Review, Vol. 10, No. 5, 09.2003, p. 501-505.

Research output: Contribution to journalArticle

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