TY - GEN
T1 - Effect of surface electrostatic interaction on sampling behavior of solute molecules at micro/extended-nano interface
AU - Okamoto, Kazuma
AU - Kazoe, Yutaka
AU - Mawatari, Kazuma
AU - Kitamori, Takehiko
N1 - Funding Information:
This work was supported by JST CREST Grant Number JPMJCR14G1, Japan.
PY - 2020
Y1 - 2020
N2 - We revealed that, in nanochannels with increased surface-to-volute ratio, surface electrostatic interactions restrict motion of solute molecules, and they significantly affect injection of solute molecules from micro to nanochannel by pressure-driven flow. 100% solute injection to the nanochannel was achieved in case of the solute without electric charge. The results indicate that uniform sampling from micro to nanochannel is prevented by the electrostatic interactions, and this can lead to significant bias of analytical results in nanofluidic devices. Accordingly, this study provides important knowledge for conceptual design of nanofluidic devices for analysis and ultra-high efficient separation.
AB - We revealed that, in nanochannels with increased surface-to-volute ratio, surface electrostatic interactions restrict motion of solute molecules, and they significantly affect injection of solute molecules from micro to nanochannel by pressure-driven flow. 100% solute injection to the nanochannel was achieved in case of the solute without electric charge. The results indicate that uniform sampling from micro to nanochannel is prevented by the electrostatic interactions, and this can lead to significant bias of analytical results in nanofluidic devices. Accordingly, this study provides important knowledge for conceptual design of nanofluidic devices for analysis and ultra-high efficient separation.
KW - Electrostatic interaction
KW - Extended-nano space
KW - Injection
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M3 - Conference contribution
AN - SCOPUS:85079647556
T3 - 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
SP - 279
EP - 280
BT - 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
PB - Chemical and Biological Microsystems Society
T2 - 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
Y2 - 22 October 2017 through 26 October 2017
ER -