Effect of surface electrostatic interaction on sampling behavior of solute molecules at micro/extended-nano interface

Kazuma Okamoto, Yutaka Kazoe, Kazuma Mawatari, Takehiko Kitamori

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We revealed that, in nanochannels with increased surface-to-volute ratio, surface electrostatic interactions restrict motion of solute molecules, and they significantly affect injection of solute molecules from micro to nanochannel by pressure-driven flow. 100% solute injection to the nanochannel was achieved in case of the solute without electric charge. The results indicate that uniform sampling from micro to nanochannel is prevented by the electrostatic interactions, and this can lead to significant bias of analytical results in nanofluidic devices. Accordingly, this study provides important knowledge for conceptual design of nanofluidic devices for analysis and ultra-high efficient separation.

Original languageEnglish
Title of host publication21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
PublisherChemical and Biological Microsystems Society
Pages279-280
Number of pages2
ISBN (Electronic)9780692941836
Publication statusPublished - 2020 Jan 1
Externally publishedYes
Event21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 - Savannah, United States
Duration: 2017 Oct 222017 Oct 26

Publication series

Name21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

Conference

Conference21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
CountryUnited States
CitySavannah
Period17/10/2217/10/26

Keywords

  • Electrostatic interaction
  • Extended-nano space
  • Injection

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Okamoto, K., Kazoe, Y., Mawatari, K., & Kitamori, T. (2020). Effect of surface electrostatic interaction on sampling behavior of solute molecules at micro/extended-nano interface. In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 (pp. 279-280). (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017). Chemical and Biological Microsystems Society.