Abstract
We revealed that, in nanochannels with increased surface-to-volute ratio, surface electrostatic interactions restrict motion of solute molecules, and they significantly affect injection of solute molecules from micro to nanochannel by pressure-driven flow. 100% solute injection to the nanochannel was achieved in case of the solute without electric charge. The results indicate that uniform sampling from micro to nanochannel is prevented by the electrostatic interactions, and this can lead to significant bias of analytical results in nanofluidic devices. Accordingly, this study provides important knowledge for conceptual design of nanofluidic devices for analysis and ultra-high efficient separation.
| Original language | English |
|---|---|
| Title of host publication | 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 279-280 |
| Number of pages | 2 |
| ISBN (Electronic) | 9780692941836 |
| Publication status | Published - 2020 Jan 1 |
| Externally published | Yes |
| Event | 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 - Savannah, United States Duration: 2017 Oct 22 → 2017 Oct 26 |
Publication series
| Name | 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 |
|---|
Conference
| Conference | 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 |
|---|---|
| Country | United States |
| City | Savannah |
| Period | 17/10/22 → 17/10/26 |
Keywords
- Electrostatic interaction
- Extended-nano space
- Injection
ASJC Scopus subject areas
- Chemical Engineering (miscellaneous)
- Bioengineering
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Cite this
Okamoto, K., Kazoe, Y., Mawatari, K., & Kitamori, T. (2020). Effect of surface electrostatic interaction on sampling behavior of solute molecules at micro/extended-nano interface. In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 (pp. 279-280). (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017). Chemical and Biological Microsystems Society.