Effect of the Japanese herbal kampo medicine Dai-kenchu-to on postoperative adhesive small bowel obstruction requiring long-tube decompression: A propensity score analysis

Hideo Yasunaga, Hiroaki Miyata, Hiromasa Horiguchi, Kazuaki Kuwabara, Hideki Hashimoto, Shinya Matsuda

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Adhesive small bowel obstruction (ASBO) is an adverse consequence of abdominal surgery. Although the Kampo medicine Dai-kenchu-to is widely used in Japan for treatment of postoperative ASBO, rigorous clinical studies for its use have not been performed. In the present retrospective observational study using the Japanese diagnosis procedure combination inpatient database, we selected 288 propensity-score-matched patients with early postoperative ASBO following colorectal cancer surgery, who received long-tube decompression (LTD) with or without Dai-kenchu-to administration. The success rates of LTD were not significantly different between Dai-kenchu-to users and nonusers (84.7 versus 78.5; P=.224), while Dai-kenchu-to users showed a shorter duration of LTD (8 versus 10 days; P=.012), shorter duration between long-tube insertion and discharge (23 versus 25 days; P=.018), and lower hospital charges ($ 23,086 versus dollar;26,950; P=.018) compared with Dai-kenchu-to nonusers. In conclusion, the present study suggests that Dai-kenchu-to is effective for reducing the duration of LTD and saving costs.

Original languageEnglish
Article number264289
JournalEvidence-based Complementary and Alternative Medicine
Volume2011
DOIs
Publication statusPublished - 2011
Externally publishedYes

Fingerprint

Kampo Medicine
Propensity Score
Herbal Medicine
Decompression
Adhesives
Hospital Charges
Colorectal Surgery
Observational Studies
dai-kenchu-to
Inpatients
Colorectal Neoplasms
Japan
Retrospective Studies
Databases
Costs and Cost Analysis

ASJC Scopus subject areas

  • Complementary and alternative medicine

Cite this

Effect of the Japanese herbal kampo medicine Dai-kenchu-to on postoperative adhesive small bowel obstruction requiring long-tube decompression : A propensity score analysis. / Yasunaga, Hideo; Miyata, Hiroaki; Horiguchi, Hiromasa; Kuwabara, Kazuaki; Hashimoto, Hideki; Matsuda, Shinya.

In: Evidence-based Complementary and Alternative Medicine, Vol. 2011, 264289, 2011.

Research output: Contribution to journalArticle

@article{77e6b19d83714ea69fdb7f5116a8f4cc,
title = "Effect of the Japanese herbal kampo medicine Dai-kenchu-to on postoperative adhesive small bowel obstruction requiring long-tube decompression: A propensity score analysis",
abstract = "Adhesive small bowel obstruction (ASBO) is an adverse consequence of abdominal surgery. Although the Kampo medicine Dai-kenchu-to is widely used in Japan for treatment of postoperative ASBO, rigorous clinical studies for its use have not been performed. In the present retrospective observational study using the Japanese diagnosis procedure combination inpatient database, we selected 288 propensity-score-matched patients with early postoperative ASBO following colorectal cancer surgery, who received long-tube decompression (LTD) with or without Dai-kenchu-to administration. The success rates of LTD were not significantly different between Dai-kenchu-to users and nonusers (84.7 versus 78.5; P=.224), while Dai-kenchu-to users showed a shorter duration of LTD (8 versus 10 days; P=.012), shorter duration between long-tube insertion and discharge (23 versus 25 days; P=.018), and lower hospital charges ($ 23,086 versus dollar;26,950; P=.018) compared with Dai-kenchu-to nonusers. In conclusion, the present study suggests that Dai-kenchu-to is effective for reducing the duration of LTD and saving costs.",
author = "Hideo Yasunaga and Hiroaki Miyata and Hiromasa Horiguchi and Kazuaki Kuwabara and Hideki Hashimoto and Shinya Matsuda",
year = "2011",
doi = "10.1155/2011/264289",
language = "English",
volume = "2011",
journal = "Evidence-based Complementary and Alternative Medicine",
issn = "1741-427X",
publisher = "Hindawi Publishing Corporation",

}

TY - JOUR

T1 - Effect of the Japanese herbal kampo medicine Dai-kenchu-to on postoperative adhesive small bowel obstruction requiring long-tube decompression

T2 - A propensity score analysis

AU - Yasunaga, Hideo

AU - Miyata, Hiroaki

AU - Horiguchi, Hiromasa

AU - Kuwabara, Kazuaki

AU - Hashimoto, Hideki

AU - Matsuda, Shinya

PY - 2011

Y1 - 2011

N2 - Adhesive small bowel obstruction (ASBO) is an adverse consequence of abdominal surgery. Although the Kampo medicine Dai-kenchu-to is widely used in Japan for treatment of postoperative ASBO, rigorous clinical studies for its use have not been performed. In the present retrospective observational study using the Japanese diagnosis procedure combination inpatient database, we selected 288 propensity-score-matched patients with early postoperative ASBO following colorectal cancer surgery, who received long-tube decompression (LTD) with or without Dai-kenchu-to administration. The success rates of LTD were not significantly different between Dai-kenchu-to users and nonusers (84.7 versus 78.5; P=.224), while Dai-kenchu-to users showed a shorter duration of LTD (8 versus 10 days; P=.012), shorter duration between long-tube insertion and discharge (23 versus 25 days; P=.018), and lower hospital charges ($ 23,086 versus dollar;26,950; P=.018) compared with Dai-kenchu-to nonusers. In conclusion, the present study suggests that Dai-kenchu-to is effective for reducing the duration of LTD and saving costs.

AB - Adhesive small bowel obstruction (ASBO) is an adverse consequence of abdominal surgery. Although the Kampo medicine Dai-kenchu-to is widely used in Japan for treatment of postoperative ASBO, rigorous clinical studies for its use have not been performed. In the present retrospective observational study using the Japanese diagnosis procedure combination inpatient database, we selected 288 propensity-score-matched patients with early postoperative ASBO following colorectal cancer surgery, who received long-tube decompression (LTD) with or without Dai-kenchu-to administration. The success rates of LTD were not significantly different between Dai-kenchu-to users and nonusers (84.7 versus 78.5; P=.224), while Dai-kenchu-to users showed a shorter duration of LTD (8 versus 10 days; P=.012), shorter duration between long-tube insertion and discharge (23 versus 25 days; P=.018), and lower hospital charges ($ 23,086 versus dollar;26,950; P=.018) compared with Dai-kenchu-to nonusers. In conclusion, the present study suggests that Dai-kenchu-to is effective for reducing the duration of LTD and saving costs.

UR - http://www.scopus.com/inward/record.url?scp=79959241171&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79959241171&partnerID=8YFLogxK

U2 - 10.1155/2011/264289

DO - 10.1155/2011/264289

M3 - Article

C2 - 21584269

AN - SCOPUS:79959241171

VL - 2011

JO - Evidence-based Complementary and Alternative Medicine

JF - Evidence-based Complementary and Alternative Medicine

SN - 1741-427X

M1 - 264289

ER -