Effect of thickness of superficial tissues on the spatial sensitivity profile for optical imaging

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

It is important for near-infrared imaging to estimate the sensitivity of detected signal to the change in absorption of tissue resulting from brain activation and the volume of tissue interrogated for a specific source-detector spacing. In this study, light propagation in adult head models is predicted by Monte Carlo simulation in order to investigate the effect of the thickness of the superficial tissues on the partial optical path length in the brain and on the spatial sensitivity profile. The effect of thickness of skull on the partial optical path length and spatial sensitivity profile is almost the same as that of the scalp. The effect of thickness of cerebrospinal fluid layer on the partial optical path length and spatial sensitivity profile is different from that of the scalp and skull. The partial optical path length mainly depends upon the depth of inner skull surface whilst the spatial sensitivity profile is considerably affected by the thickness of the cerebrospinal fluid layer.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsD.A. Boas
Pages160-167
Number of pages8
Volume5138
Publication statusPublished - 2003
EventPhoton Migration and Diffuse-Light Imaging - Munich, Germany
Duration: 2003 Jun 222003 Jun 23

Other

OtherPhoton Migration and Diffuse-Light Imaging
CountryGermany
CityMunich
Period03/6/2203/6/23

Fingerprint

Cerebrospinal fluid
optical paths
skull
Tissue
Imaging techniques
sensitivity
Brain
cerebrospinal fluid
profiles
Light propagation
Infrared imaging
brain
Chemical activation
Detectors
spacing
activation
propagation
detectors
estimates
simulation

Keywords

  • Near infrared spectroscopy
  • Spatial sensitivity profile
  • Topographic imaging

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Okada, E. (2003). Effect of thickness of superficial tissues on the spatial sensitivity profile for optical imaging. In D. A. Boas (Ed.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 5138, pp. 160-167)

Effect of thickness of superficial tissues on the spatial sensitivity profile for optical imaging. / Okada, Eiji.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / D.A. Boas. Vol. 5138 2003. p. 160-167.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Okada, E 2003, Effect of thickness of superficial tissues on the spatial sensitivity profile for optical imaging. in DA Boas (ed.), Proceedings of SPIE - The International Society for Optical Engineering. vol. 5138, pp. 160-167, Photon Migration and Diffuse-Light Imaging, Munich, Germany, 03/6/22.
Okada E. Effect of thickness of superficial tissues on the spatial sensitivity profile for optical imaging. In Boas DA, editor, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 5138. 2003. p. 160-167
Okada, Eiji. / Effect of thickness of superficial tissues on the spatial sensitivity profile for optical imaging. Proceedings of SPIE - The International Society for Optical Engineering. editor / D.A. Boas. Vol. 5138 2003. pp. 160-167
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