Effective multidisciplinary treatment for ovarian granulosa cell tumor with multiple metastases - A case report

W. Yamagami, S. Ooki, H. Semba, T. Ninomiya, S. Hayashi, H. Yamashita, H. Arai

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Ovarian granulosa cell tumor (GCT) is among the ovarian sex-cord stromal tumors that are classified as borderline malignancies. We report a case of GCT with multiple metastases for which multidisciplinary treatment including surgery, chemotherapy and radiotherapy was effective. A 41-year-old woman underwent left salpingo-oophorectomy because of an ovarian tumor in 2004. Final pathology confirmed a granulosa cell tumor adult type, FIGO Stage IC. In 2008, tumorectomy of the lower abdominal wall metastases was also performed. After three cycles of BEP chemotherapy for metastases of the right lung, liver, paraaortic lymph node and rectus, surgical resection was performed in 2009. In 2010, local radiation was performed for the first lumbar vertebral metastasis. Ovarian GCTs exhibit slow growth but if the surgical stage is IC or higher, there is the possibility of recurrence. It is important to treat recurrent tumors with the combination of surgery, chemotherapy, and radiation therapy.

Original languageEnglish
Pages (from-to)370-375
Number of pages6
JournalEuropean Journal of Gynaecological Oncology
Volume33
Issue number4
Publication statusPublished - 2012

Keywords

  • BEP
  • Ovarian granulosa cell tumor
  • Recurrence

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynaecology

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