Effects of a Helicobacter pylori eradication regimen on anti-platelet autoantibody response in infected and uninfected patients with idiopathic thrombocytopenic purpura

Atsuko Asahi, Masataka Kuwana, Hidekazu Suzuki, Toshifumi Hibi, Yutaka Kawakami, Yasuo Ikeda

Research output: Contribution to journalArticlepeer-review

46 Citations (Scopus)

Abstract

Thirty-seven patients with idiopathic thrombocytopenic purpura (TTP) were treated with a standard Helicobacter pylori eradication regimen irrespective of H. pylori infection. Our results indicate that platelet recovery results from the disappearance of H. pylori itself, and is mediated, in part, through suppression of anti-platelet autoantibody production.

Original languageEnglish
Pages (from-to)1436-1437
Number of pages2
JournalHaematologica
Volume91
Issue number10
Publication statusPublished - 2006 Oct 1

Keywords

  • Autoantibody
  • Helicobacter pylori
  • Idiopathic thrombocytopenic purpura
  • Platelet

ASJC Scopus subject areas

  • Hematology

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