Effects of a perilymphatic fistula on the passive vibration response of the basilar membrane

Takuji Koike, Chiaki Sakamoto, Tasuku Sakashita, Ken Hayashi, Sho Kanzaki, Kaoru Ogawa

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

In this study, a three-dimensional finite-element model of the passive human cochlea was created. Dynamic behavior of the basilar membrane caused by the vibration of the stapes footplate was analyzed considering a fluid-structure interaction with the cochlear fluid. Next, the effects of a perilymphatic fistula (PLF) on the vibration of the cochlea were examined by making a small hole on the wall of the cochlea model. Even if a PLF existed in the scala vestibuli, a traveling wave was generated on the basilar membrane. When a PLF existed at the basal end of the cochlea, the shape of the traveling wave envelope showed no remarkable change, but the maximum amplitude became smaller at the entire frequency range from 0.5 to 5. kHz and decreased with decreasing frequency. In contrast, when a PLF existed at the second turn of the cochlea, the traveling wave envelope showed a notch at the position of the PLF and the maximum amplitude also became smaller. This model assists in elucidating the mechanisms of hearing loss due to a PLF from the view of dynamics.

Original languageEnglish
Pages (from-to)117-125
Number of pages9
JournalHearing Research
Volume283
Issue number1-2
DOIs
Publication statusPublished - 2012 Jan

Fingerprint

Basilar Membrane
Cochlea
Vibration
Fistula
Scala Vestibuli
Stapes
Hearing Loss

ASJC Scopus subject areas

  • Sensory Systems

Cite this

Effects of a perilymphatic fistula on the passive vibration response of the basilar membrane. / Koike, Takuji; Sakamoto, Chiaki; Sakashita, Tasuku; Hayashi, Ken; Kanzaki, Sho; Ogawa, Kaoru.

In: Hearing Research, Vol. 283, No. 1-2, 01.2012, p. 117-125.

Research output: Contribution to journalArticle

Koike, Takuji ; Sakamoto, Chiaki ; Sakashita, Tasuku ; Hayashi, Ken ; Kanzaki, Sho ; Ogawa, Kaoru. / Effects of a perilymphatic fistula on the passive vibration response of the basilar membrane. In: Hearing Research. 2012 ; Vol. 283, No. 1-2. pp. 117-125.
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