Effects of artificial tear temperature on corneal sensation and subjective comfort

Hiroshi Fujishima, Yukiko Yagi, Jun Shimazaki, Kazuo Tsubota

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Purpose. Cooling reduces acute inflammation and local nerve sensation. We investigated the relationship between artificial tear temperature, ocular surface sensation, and patient comfort. Methods. We placed preservative-free artificial tears and eye mask stored at four temperatures (36°C, 25.2°C, 4°C, and -10°C) in the right eyes of 24 normal subjects, whose left eyes served as controls. Corneal and conjunctival sensations were measured and corneal temperature was recorded. Comfort was reported on a 7-point scale. Results. Corneal temperature was significantly lowered with all temperature artificial tears and frozen eye mask (p < 0.001 for each temperature relative to the previous one). Aesthesiometer readings were inversely correlated with corneal temperature (r = -0.45, p = 0.0005), decreasing with lower temperatures, reaching 2.0±1.3 g/mm2 (p = 0.001) for the mask. Conjunctival sensation reacted similarly and was well correlated with both corneal temperature (r = 0.43, p = 0.0009) and corneal sensation (r = 0.39, p = 0.006). Treatments provided relief, with the 4°C tears being the most comfortable (p = 0.0001). Conclusion. Although there may still be some biases, cooled artificial tears provide relief to the eye by the mechanism of reduced corneal and conjunctival sensation.

Original languageEnglish
Pages (from-to)630-634
Number of pages5
JournalCornea
Volume16
Issue number6
Publication statusPublished - 1997 Nov

Fingerprint

Temperature
Masks
Artificial Eye
Lubricant Eye Drops
Tears
Reading
Inflammation

Keywords

  • Comfort
  • Conjunctival sensation
  • Cooling
  • Corneal sensation
  • Corneal temperature

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Effects of artificial tear temperature on corneal sensation and subjective comfort. / Fujishima, Hiroshi; Yagi, Yukiko; Shimazaki, Jun; Tsubota, Kazuo.

In: Cornea, Vol. 16, No. 6, 11.1997, p. 630-634.

Research output: Contribution to journalArticle

Fujishima, H, Yagi, Y, Shimazaki, J & Tsubota, K 1997, 'Effects of artificial tear temperature on corneal sensation and subjective comfort', Cornea, vol. 16, no. 6, pp. 630-634.
Fujishima, Hiroshi ; Yagi, Yukiko ; Shimazaki, Jun ; Tsubota, Kazuo. / Effects of artificial tear temperature on corneal sensation and subjective comfort. In: Cornea. 1997 ; Vol. 16, No. 6. pp. 630-634.
@article{c1943c5b00b642c4bc562fc7ee0c143e,
title = "Effects of artificial tear temperature on corneal sensation and subjective comfort",
abstract = "Purpose. Cooling reduces acute inflammation and local nerve sensation. We investigated the relationship between artificial tear temperature, ocular surface sensation, and patient comfort. Methods. We placed preservative-free artificial tears and eye mask stored at four temperatures (36°C, 25.2°C, 4°C, and -10°C) in the right eyes of 24 normal subjects, whose left eyes served as controls. Corneal and conjunctival sensations were measured and corneal temperature was recorded. Comfort was reported on a 7-point scale. Results. Corneal temperature was significantly lowered with all temperature artificial tears and frozen eye mask (p < 0.001 for each temperature relative to the previous one). Aesthesiometer readings were inversely correlated with corneal temperature (r = -0.45, p = 0.0005), decreasing with lower temperatures, reaching 2.0±1.3 g/mm2 (p = 0.001) for the mask. Conjunctival sensation reacted similarly and was well correlated with both corneal temperature (r = 0.43, p = 0.0009) and corneal sensation (r = 0.39, p = 0.006). Treatments provided relief, with the 4°C tears being the most comfortable (p = 0.0001). Conclusion. Although there may still be some biases, cooled artificial tears provide relief to the eye by the mechanism of reduced corneal and conjunctival sensation.",
keywords = "Comfort, Conjunctival sensation, Cooling, Corneal sensation, Corneal temperature",
author = "Hiroshi Fujishima and Yukiko Yagi and Jun Shimazaki and Kazuo Tsubota",
year = "1997",
month = "11",
language = "English",
volume = "16",
pages = "630--634",
journal = "Cornea",
issn = "0277-3740",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

TY - JOUR

T1 - Effects of artificial tear temperature on corneal sensation and subjective comfort

AU - Fujishima, Hiroshi

AU - Yagi, Yukiko

AU - Shimazaki, Jun

AU - Tsubota, Kazuo

PY - 1997/11

Y1 - 1997/11

N2 - Purpose. Cooling reduces acute inflammation and local nerve sensation. We investigated the relationship between artificial tear temperature, ocular surface sensation, and patient comfort. Methods. We placed preservative-free artificial tears and eye mask stored at four temperatures (36°C, 25.2°C, 4°C, and -10°C) in the right eyes of 24 normal subjects, whose left eyes served as controls. Corneal and conjunctival sensations were measured and corneal temperature was recorded. Comfort was reported on a 7-point scale. Results. Corneal temperature was significantly lowered with all temperature artificial tears and frozen eye mask (p < 0.001 for each temperature relative to the previous one). Aesthesiometer readings were inversely correlated with corneal temperature (r = -0.45, p = 0.0005), decreasing with lower temperatures, reaching 2.0±1.3 g/mm2 (p = 0.001) for the mask. Conjunctival sensation reacted similarly and was well correlated with both corneal temperature (r = 0.43, p = 0.0009) and corneal sensation (r = 0.39, p = 0.006). Treatments provided relief, with the 4°C tears being the most comfortable (p = 0.0001). Conclusion. Although there may still be some biases, cooled artificial tears provide relief to the eye by the mechanism of reduced corneal and conjunctival sensation.

AB - Purpose. Cooling reduces acute inflammation and local nerve sensation. We investigated the relationship between artificial tear temperature, ocular surface sensation, and patient comfort. Methods. We placed preservative-free artificial tears and eye mask stored at four temperatures (36°C, 25.2°C, 4°C, and -10°C) in the right eyes of 24 normal subjects, whose left eyes served as controls. Corneal and conjunctival sensations were measured and corneal temperature was recorded. Comfort was reported on a 7-point scale. Results. Corneal temperature was significantly lowered with all temperature artificial tears and frozen eye mask (p < 0.001 for each temperature relative to the previous one). Aesthesiometer readings were inversely correlated with corneal temperature (r = -0.45, p = 0.0005), decreasing with lower temperatures, reaching 2.0±1.3 g/mm2 (p = 0.001) for the mask. Conjunctival sensation reacted similarly and was well correlated with both corneal temperature (r = 0.43, p = 0.0009) and corneal sensation (r = 0.39, p = 0.006). Treatments provided relief, with the 4°C tears being the most comfortable (p = 0.0001). Conclusion. Although there may still be some biases, cooled artificial tears provide relief to the eye by the mechanism of reduced corneal and conjunctival sensation.

KW - Comfort

KW - Conjunctival sensation

KW - Cooling

KW - Corneal sensation

KW - Corneal temperature

UR - http://www.scopus.com/inward/record.url?scp=0030786029&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030786029&partnerID=8YFLogxK

M3 - Article

C2 - 9395871

AN - SCOPUS:0030786029

VL - 16

SP - 630

EP - 634

JO - Cornea

JF - Cornea

SN - 0277-3740

IS - 6

ER -