Effects of pedaling exercise on the intracortical inhibition of cortical leg area

Tomofumi Yamaguchi, Toshiyuki Fujiwara, William Liu, Meigen Liu

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Pedaling is widely used for rehabilitation of locomotion because it induces similar muscle activity to that observed during locomotion. However, no study has examined the effects of pedaling exercise on intracortical inhibition. The aim of the present study was to investigate the effect of pedaling exercise on short-interval intracortical inhibition (SICI) in the cortical area controlling the tibialis anterior (TA) and soleus (SOL) muscles. Ten healthy adults participated in this study and were instructed to perform 7 min of active and passive pedaling. Paired pulse transcranial magnetic stimulation (TMS) was used to investigate the SICI. Using interstimulus intervals of 2-3 ms, the SICI of TA and SOL muscles was recorded at rest before and after the pedaling and repetitive ankle dorsiflexion tasks. SICI in both TA and SOL muscles decreased immediately after active pedaling. There were no significant changes in SICI after the passive pedaling and repetitive ankle dorsiflexion. A short-term, low-intensity active pedaling exercise decreases the intracortical inhibition of the leg area of the motor cortex. Our results suggest that pedaling has the potential to restore ambulation-inducing cortical reorganization among patients with central nervous system lesions.

Original languageEnglish
Pages (from-to)401-406
Number of pages6
JournalExperimental Brain Research
Volume218
Issue number3
DOIs
Publication statusPublished - 2012 May

Fingerprint

Foot
Leg
Exercise
Skeletal Muscle
Locomotion
Ankle
Transcranial Magnetic Stimulation
Motor Cortex
Walking
Rehabilitation
Central Nervous System
Muscles

Keywords

  • Lower extremity
  • Motor cortex
  • Transcranial magnetic stimulation

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Effects of pedaling exercise on the intracortical inhibition of cortical leg area. / Yamaguchi, Tomofumi; Fujiwara, Toshiyuki; Liu, William; Liu, Meigen.

In: Experimental Brain Research, Vol. 218, No. 3, 05.2012, p. 401-406.

Research output: Contribution to journalArticle

Yamaguchi, Tomofumi ; Fujiwara, Toshiyuki ; Liu, William ; Liu, Meigen. / Effects of pedaling exercise on the intracortical inhibition of cortical leg area. In: Experimental Brain Research. 2012 ; Vol. 218, No. 3. pp. 401-406.
@article{829e26603df64d3aa220677952aeaf50,
title = "Effects of pedaling exercise on the intracortical inhibition of cortical leg area",
abstract = "Pedaling is widely used for rehabilitation of locomotion because it induces similar muscle activity to that observed during locomotion. However, no study has examined the effects of pedaling exercise on intracortical inhibition. The aim of the present study was to investigate the effect of pedaling exercise on short-interval intracortical inhibition (SICI) in the cortical area controlling the tibialis anterior (TA) and soleus (SOL) muscles. Ten healthy adults participated in this study and were instructed to perform 7 min of active and passive pedaling. Paired pulse transcranial magnetic stimulation (TMS) was used to investigate the SICI. Using interstimulus intervals of 2-3 ms, the SICI of TA and SOL muscles was recorded at rest before and after the pedaling and repetitive ankle dorsiflexion tasks. SICI in both TA and SOL muscles decreased immediately after active pedaling. There were no significant changes in SICI after the passive pedaling and repetitive ankle dorsiflexion. A short-term, low-intensity active pedaling exercise decreases the intracortical inhibition of the leg area of the motor cortex. Our results suggest that pedaling has the potential to restore ambulation-inducing cortical reorganization among patients with central nervous system lesions.",
keywords = "Lower extremity, Motor cortex, Transcranial magnetic stimulation",
author = "Tomofumi Yamaguchi and Toshiyuki Fujiwara and William Liu and Meigen Liu",
year = "2012",
month = "5",
doi = "10.1007/s00221-012-3026-7",
language = "English",
volume = "218",
pages = "401--406",
journal = "Experimental Brain Research",
issn = "0014-4819",
publisher = "Springer Verlag",
number = "3",

}

TY - JOUR

T1 - Effects of pedaling exercise on the intracortical inhibition of cortical leg area

AU - Yamaguchi, Tomofumi

AU - Fujiwara, Toshiyuki

AU - Liu, William

AU - Liu, Meigen

PY - 2012/5

Y1 - 2012/5

N2 - Pedaling is widely used for rehabilitation of locomotion because it induces similar muscle activity to that observed during locomotion. However, no study has examined the effects of pedaling exercise on intracortical inhibition. The aim of the present study was to investigate the effect of pedaling exercise on short-interval intracortical inhibition (SICI) in the cortical area controlling the tibialis anterior (TA) and soleus (SOL) muscles. Ten healthy adults participated in this study and were instructed to perform 7 min of active and passive pedaling. Paired pulse transcranial magnetic stimulation (TMS) was used to investigate the SICI. Using interstimulus intervals of 2-3 ms, the SICI of TA and SOL muscles was recorded at rest before and after the pedaling and repetitive ankle dorsiflexion tasks. SICI in both TA and SOL muscles decreased immediately after active pedaling. There were no significant changes in SICI after the passive pedaling and repetitive ankle dorsiflexion. A short-term, low-intensity active pedaling exercise decreases the intracortical inhibition of the leg area of the motor cortex. Our results suggest that pedaling has the potential to restore ambulation-inducing cortical reorganization among patients with central nervous system lesions.

AB - Pedaling is widely used for rehabilitation of locomotion because it induces similar muscle activity to that observed during locomotion. However, no study has examined the effects of pedaling exercise on intracortical inhibition. The aim of the present study was to investigate the effect of pedaling exercise on short-interval intracortical inhibition (SICI) in the cortical area controlling the tibialis anterior (TA) and soleus (SOL) muscles. Ten healthy adults participated in this study and were instructed to perform 7 min of active and passive pedaling. Paired pulse transcranial magnetic stimulation (TMS) was used to investigate the SICI. Using interstimulus intervals of 2-3 ms, the SICI of TA and SOL muscles was recorded at rest before and after the pedaling and repetitive ankle dorsiflexion tasks. SICI in both TA and SOL muscles decreased immediately after active pedaling. There were no significant changes in SICI after the passive pedaling and repetitive ankle dorsiflexion. A short-term, low-intensity active pedaling exercise decreases the intracortical inhibition of the leg area of the motor cortex. Our results suggest that pedaling has the potential to restore ambulation-inducing cortical reorganization among patients with central nervous system lesions.

KW - Lower extremity

KW - Motor cortex

KW - Transcranial magnetic stimulation

UR - http://www.scopus.com/inward/record.url?scp=84862874337&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84862874337&partnerID=8YFLogxK

U2 - 10.1007/s00221-012-3026-7

DO - 10.1007/s00221-012-3026-7

M3 - Article

C2 - 22349500

AN - SCOPUS:84862874337

VL - 218

SP - 401

EP - 406

JO - Experimental Brain Research

JF - Experimental Brain Research

SN - 0014-4819

IS - 3

ER -