Effects of transcranial stimulating electrode montages over the head for lower-extremity transcranial motor evoked potential monitoring

Ryosuke Tomio, Takenori Akiyama, Takayuki Oohira, Kazunari Yoshida

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

OBJECTIVE The aim of this study was to determine the most effective electrode montage to elicit lower-extremity transcranial motor evoked potentials (LE-TMEPs) using a minimum stimulation current. METHODS A realistic 3D head model was created from T1-weighted images. Finite element methods were used to visualize the electric field in the brain, which was generated by transcranial electrical stimulation via 4 electrode montage models. The stimulation threshold level of LE-TMEPs in 52 patients was also studied in a practical clinical setting to determine the effects of each electrode montage. RESULTS The electric field in the brain radially diffused from the brain surface at a maximum just below the electrodes in the finite element models. The Cz-inion electrode montage generated a centrally distributed high electric field with a current direction longitudinal and parallel to most of the pyramidal tract fibers of the lower extremity. These features seemed to be effective in igniting LE-TMEPs. Threshold level recordings of LE-TMEPs revealed that the Cz-inion electrode montage had a lower threshold on average than the C3-C4 montage, 76.5 20.6 mA and 86.2 20.6 mA, respectively (31 patients, t = 4.045, p < 0.001, paired t-Test). In 23 (74.2%) of 31 cases, the Cz-inion montage could elicit LE-TMEPs at a lower threshold than C3-C4. CONCLUSIONS The C3-C4 and C1-C2 electrode montages are the standard for tMEP monitoring in neurosurgery, but the Cz-inion montage showed lower thresholds for the generation of LE-TMEPs. The Cz-inion electrode montage should be a good alternative for LE-TMEP monitoring when the C3-C4 has trouble igniting LE-TMEPs.

Original languageEnglish
Pages (from-to)1951-1958
Number of pages8
JournalJournal of Neurosurgery
Volume126
Issue number6
DOIs
Publication statusPublished - 2017 Jun 1

Keywords

  • Diagnostic and operative techniques
  • Electrode montage
  • Lower extremity
  • Neurosurgery
  • Transcranial electric stimulation
  • Transcranial motor evoked potential

ASJC Scopus subject areas

  • Surgery
  • Medicine(all)
  • Clinical Neurology

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