Efficient and stereoselective synthesis of the disaccharide fragment of incednine

Takashi Ohtani, Shohei Sakai, Akira Takada, Daisuke Takahashi, Kazunobu Toshima

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Efficient and stereoselective synthesis of a disaccharide fragment, 2-deoxy-4-O-(N′-monodemethyl-d-forosaminyl)-2-methylamino-β-d- xylopyranoside, of a novel antibiotic, incednine (1), is described. The key β-stereoselective formation of a 2,3,4,6-tetradeoxy-4-methylamino glycoside bond was achieved by remote participation-assisted glycosylation.

Original languageEnglish
Pages (from-to)6126-6129
Number of pages4
JournalOrganic Letters
Volume13
Issue number22
DOIs
Publication statusPublished - 2011 Nov 18

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Glycosylation
glucosides
antibiotics
Disaccharides
Glycosides
fragments
Anti-Bacterial Agents
synthesis
incednine

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Efficient and stereoselective synthesis of the disaccharide fragment of incednine. / Ohtani, Takashi; Sakai, Shohei; Takada, Akira; Takahashi, Daisuke; Toshima, Kazunobu.

In: Organic Letters, Vol. 13, No. 22, 18.11.2011, p. 6126-6129.

Research output: Contribution to journalArticle

Ohtani, Takashi ; Sakai, Shohei ; Takada, Akira ; Takahashi, Daisuke ; Toshima, Kazunobu. / Efficient and stereoselective synthesis of the disaccharide fragment of incednine. In: Organic Letters. 2011 ; Vol. 13, No. 22. pp. 6126-6129.
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