Efficient preparation of C2-symmetrical chiral ferrocenyl diols by catalytic enantioselective reduction of diacylferrocenes

Hirohide Sato; Hiroto Watanabe; Yuhki Ohtsuka; Taketo Ikeno; Shin Ichi Fukuzawa; Tohru Yamada

doi:10.1021/ol0266018

Efficient preparation of C₂-symmetrical chiral ferrocenyl diols by catalytic enantioselective reduction of diacylferrocenes

Hirohide Sato, Hiroto Watanabe, Yuhki Ohtsuka, Taketo Ikeno, Shin Ichi Fukuzawa, Tohru Yamada

Department of Chemistry

Research output: Contribution to journal › Article

26 Citations (Scopus)

Abstract

equation presented Enantioselective borohydride reduction, catalyzed by the optically active β-ketoiminato cobalt(III) complex, was successfully applied to the 1,1′-dialkanoyl- and 1,1′-dibenzoylferrocenes to afford the corresponding C₂-symmetrical chiral ferrocenyl diols with high diastereoselectivity and excellent enantioselectivity.

Original language	English
Pages (from-to)	3313-3316
Number of pages	4
Journal	Organic Letters
Volume	4
Issue number	19
DOIs	https://doi.org/10.1021/ol0266018
Publication status	Published - 2002 Sep 19

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Borohydrides

borohydrides

Enantioselectivity

Cobalt

cobalt

preparation

ASJC Scopus subject areas

Molecular Medicine

Cite this

Sato, H., Watanabe, H., Ohtsuka, Y., Ikeno, T., Fukuzawa, S. I., & Yamada, T. (2002). Efficient preparation of C₂-symmetrical chiral ferrocenyl diols by catalytic enantioselective reduction of diacylferrocenes. Organic Letters, 4(19), 3313-3316. https://doi.org/10.1021/ol0266018

Efficient preparation of C₂-symmetrical chiral ferrocenyl diols by catalytic enantioselective reduction of diacylferrocenes. / Sato, Hirohide; Watanabe, Hiroto; Ohtsuka, Yuhki; Ikeno, Taketo; Fukuzawa, Shin Ichi; Yamada, Tohru.

In: Organic Letters, Vol. 4, No. 19, 19.09.2002, p. 3313-3316.

Research output: Contribution to journal › Article

Sato, H, Watanabe, H, Ohtsuka, Y, Ikeno, T, Fukuzawa, SI & Yamada, T 2002, 'Efficient preparation of C₂-symmetrical chiral ferrocenyl diols by catalytic enantioselective reduction of diacylferrocenes', Organic Letters, vol. 4, no. 19, pp. 3313-3316. https://doi.org/10.1021/ol0266018

Sato H, Watanabe H, Ohtsuka Y, Ikeno T, Fukuzawa SI, Yamada T. Efficient preparation of C₂-symmetrical chiral ferrocenyl diols by catalytic enantioselective reduction of diacylferrocenes. Organic Letters. 2002 Sep 19;4(19):3313-3316. https://doi.org/10.1021/ol0266018

Sato, Hirohide ; Watanabe, Hiroto ; Ohtsuka, Yuhki ; Ikeno, Taketo ; Fukuzawa, Shin Ichi ; Yamada, Tohru. / Efficient preparation of C₂-symmetrical chiral ferrocenyl diols by catalytic enantioselective reduction of diacylferrocenes. In: Organic Letters. 2002 ; Vol. 4, No. 19. pp. 3313-3316.

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10.1021/ol0266018