Electroanalysis of sulfonamides by flow injection system/high-performance liquid chromatography coupled with amperometric detection using boron-doped diamond electrode

Anchana Preechaworapun, Suchada Chuanuwatanakul, Yasuaki Einaga, Kate Grudpan, Shoji Motomizu, Orawon Chailapakul

Research output: Contribution to journalArticlepeer-review

68 Citations (Scopus)

Abstract

Sulfonamides (SAs) were electrochemically investigated using cyclic voltammetry at a boron-doped diamond (BDD) electrode. Comparison experiments were carried out using a glassy carbon electrode. The BDD electrode provided well-resolved oxidation, irreversible cyclic voltammograms and higher current signals when compared to the glassy carbon electrode. Results obtained from using the BDD electrode in a flow injection system coupled with amperometric detection were illustrated. The optimum potential from a hydrodynamic voltammogram was found to be 1100 mV versus Ag/AgCl, which was chosen for the HPLC-amperometric system. Excellent results of linear range and detection limit were obtained. This method was also used for determination of sulfonamides in egg samples. The standard solutions of 5, 10, and 15 ppm were spiked in a real sample, and percentage of recoveries was found to be between 90.0 and 107.7.

Original languageEnglish
Pages (from-to)1726-1731
Number of pages6
JournalTalanta
Volume68
Issue number5
DOIs
Publication statusPublished - 2006 Feb 28

Keywords

  • Amperometric detection
  • Boron-doped diamond thin film electrode
  • Cyclic voltammetry
  • Flow injection system
  • HPLC
  • Sulfonamides

ASJC Scopus subject areas

  • Analytical Chemistry

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