Electrophysiological properties of the superior vena cava and venoatrial junction in patients with atrial fibrillation: Relevance to catheter ablation

Kotaro Fukumoto, Seiji Takatsuki, Takehiro Kimura, Nobuhiro Nishiyama, Kojiro Tanimoto, Yoshiyasu Aizawa, Yoko Tanimoto, Yukiko Fukuda, Shunichiro Miyoshi, Keiichi Fukuda

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Electrophysiological Properties of the Superior Vena Cava and Venoatrial Junction Background Although the superior vena cava (SVC) has been well known to be one of the important foci triggering atrial fibrillation (AF), its electrophysiological characteristics have received little research attention. The aim of this study was to investigate the electrophysiological properties of the SVC and venoatrial junction (VAJ). Methods Twenty-five consecutive AF patients without structural heart disease undergoing electrical SVC isolation were included in this study. After pulmonary vein isolation, a circular decapolar catheter and 2 multipolar catheters were emplaced in the VAJ, right atrial appendage (RAA), and SVC, respectively. Burst pacing and single extrastimulus were applied from the RAA and SVC. The atrial and caval potentials on the circular catheter in the VAJ were investigated. Results Intracaval conduction delay and various degrees of conduction block over the VAJ were observed with burst pacing from both the RAA and SVC. A single extrastimulus from the RAA and SVC with a basic cycle length of 600 milliseconds prolonged the conduction time via the VAJ by 81 ± 49.7 milliseconds and 61 ± 58.7 milliseconds, respectively. The atrial and caval electrograms at the VAJ, which were separated from each other by pacing applications, facilitated mapping of the earliest activation site at the VAJ. Conclusions Intracaval conduction delay and decremental conduction property via the VAJ were demonstrated using pacing maneuvers. Pacing applications from the RAA or SVC can help distinguish the atrial and caval potentials and can facilitate mapping of the optimal ablation sites to isolate the SVC.

Original languageEnglish
Pages (from-to)16-22
Number of pages7
JournalJournal of Cardiovascular Electrophysiology
Volume25
Issue number1
DOIs
Publication statusPublished - 2014

Fingerprint

Superior Vena Cava
Catheter Ablation
Atrial Fibrillation
Atrial Appendage
Venae Cavae
Catheters
Cardiac Electrophysiologic Techniques
Pulmonary Veins
Heart Diseases

Keywords

  • atrial fibrillation
  • catheter ablation
  • decremental conduction
  • superior vena cava
  • venoatrial junction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Electrophysiological properties of the superior vena cava and venoatrial junction in patients with atrial fibrillation : Relevance to catheter ablation. / Fukumoto, Kotaro; Takatsuki, Seiji; Kimura, Takehiro; Nishiyama, Nobuhiro; Tanimoto, Kojiro; Aizawa, Yoshiyasu; Tanimoto, Yoko; Fukuda, Yukiko; Miyoshi, Shunichiro; Fukuda, Keiichi.

In: Journal of Cardiovascular Electrophysiology, Vol. 25, No. 1, 2014, p. 16-22.

Research output: Contribution to journalArticle

Fukumoto, Kotaro ; Takatsuki, Seiji ; Kimura, Takehiro ; Nishiyama, Nobuhiro ; Tanimoto, Kojiro ; Aizawa, Yoshiyasu ; Tanimoto, Yoko ; Fukuda, Yukiko ; Miyoshi, Shunichiro ; Fukuda, Keiichi. / Electrophysiological properties of the superior vena cava and venoatrial junction in patients with atrial fibrillation : Relevance to catheter ablation. In: Journal of Cardiovascular Electrophysiology. 2014 ; Vol. 25, No. 1. pp. 16-22.
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T2 - Relevance to catheter ablation

AU - Fukumoto, Kotaro

AU - Takatsuki, Seiji

AU - Kimura, Takehiro

AU - Nishiyama, Nobuhiro

AU - Tanimoto, Kojiro

AU - Aizawa, Yoshiyasu

AU - Tanimoto, Yoko

AU - Fukuda, Yukiko

AU - Miyoshi, Shunichiro

AU - Fukuda, Keiichi

PY - 2014

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N2 - Electrophysiological Properties of the Superior Vena Cava and Venoatrial Junction Background Although the superior vena cava (SVC) has been well known to be one of the important foci triggering atrial fibrillation (AF), its electrophysiological characteristics have received little research attention. The aim of this study was to investigate the electrophysiological properties of the SVC and venoatrial junction (VAJ). Methods Twenty-five consecutive AF patients without structural heart disease undergoing electrical SVC isolation were included in this study. After pulmonary vein isolation, a circular decapolar catheter and 2 multipolar catheters were emplaced in the VAJ, right atrial appendage (RAA), and SVC, respectively. Burst pacing and single extrastimulus were applied from the RAA and SVC. The atrial and caval potentials on the circular catheter in the VAJ were investigated. Results Intracaval conduction delay and various degrees of conduction block over the VAJ were observed with burst pacing from both the RAA and SVC. A single extrastimulus from the RAA and SVC with a basic cycle length of 600 milliseconds prolonged the conduction time via the VAJ by 81 ± 49.7 milliseconds and 61 ± 58.7 milliseconds, respectively. The atrial and caval electrograms at the VAJ, which were separated from each other by pacing applications, facilitated mapping of the earliest activation site at the VAJ. Conclusions Intracaval conduction delay and decremental conduction property via the VAJ were demonstrated using pacing maneuvers. Pacing applications from the RAA or SVC can help distinguish the atrial and caval potentials and can facilitate mapping of the optimal ablation sites to isolate the SVC.

AB - Electrophysiological Properties of the Superior Vena Cava and Venoatrial Junction Background Although the superior vena cava (SVC) has been well known to be one of the important foci triggering atrial fibrillation (AF), its electrophysiological characteristics have received little research attention. The aim of this study was to investigate the electrophysiological properties of the SVC and venoatrial junction (VAJ). Methods Twenty-five consecutive AF patients without structural heart disease undergoing electrical SVC isolation were included in this study. After pulmonary vein isolation, a circular decapolar catheter and 2 multipolar catheters were emplaced in the VAJ, right atrial appendage (RAA), and SVC, respectively. Burst pacing and single extrastimulus were applied from the RAA and SVC. The atrial and caval potentials on the circular catheter in the VAJ were investigated. Results Intracaval conduction delay and various degrees of conduction block over the VAJ were observed with burst pacing from both the RAA and SVC. A single extrastimulus from the RAA and SVC with a basic cycle length of 600 milliseconds prolonged the conduction time via the VAJ by 81 ± 49.7 milliseconds and 61 ± 58.7 milliseconds, respectively. The atrial and caval electrograms at the VAJ, which were separated from each other by pacing applications, facilitated mapping of the earliest activation site at the VAJ. Conclusions Intracaval conduction delay and decremental conduction property via the VAJ were demonstrated using pacing maneuvers. Pacing applications from the RAA or SVC can help distinguish the atrial and caval potentials and can facilitate mapping of the optimal ablation sites to isolate the SVC.

KW - atrial fibrillation

KW - catheter ablation

KW - decremental conduction

KW - superior vena cava

KW - venoatrial junction

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