Embryo viscoelasticity measurement by fiber-optic system: System development and model experiment

Harumi Itoh, Tsunenori Arai, Makoto Kikuchi, Naoko Morita, Minoru Obara

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

To establish a non-invasive measurement method for human embryo viability, we studied the fiber-optic dynamic viscoelasticity measurement system. We measured the dynamic viscoelasticity of the gelatin gel model by optical monitoring of the displacement, stress and their phase difference. We measured the reflected light power change of the model surface by a single optical fiber to obtain the displacement of the surface. The dimensions of the gelatin cube model were 1×1×1 cm. A He-Ne laser with 632.8 nm in wavelength was used as a illumination light source. A thin single optical fiber with 200 μm in core diameter was used both for the illumination and detection. A solenoid-actuator was used to vibrate the model. In the surface displacement ranging from 230 μm to 400 μm, we carried out the linear relation between the reflected light power change and displacement. We measured the dynamic viscoelasticity in gelatin concentration from 2.5 % to 7.5 %. Since the dynamic viscoelasticity of the gelatin increased linearly with increasing of the gelatin concentration, the displacement obtained by the reflected light power measurement can be applicable to obtain the dynamic viscoelasticity. We demonstrated that the efficacy of the novel simple non-invasive dynamic viscoelasticity measurement using the thin optical fiber. This system may be applicable to live embryo measurement with minor reconstruction.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsR.A. Lieberman, T. Vo-Dinh
Pages89-93
Number of pages5
Volume3253
DOIs
Publication statusPublished - 1998
Externally publishedYes
EventBiomedical Sensing and Imaging Technologies - San Jose, CA, United States
Duration: 1998 Jan 261998 Jan 27

Other

OtherBiomedical Sensing and Imaging Technologies
CountryUnited States
CitySan Jose, CA
Period98/1/2698/1/27

Fingerprint

embryos
viscoelasticity
Viscoelasticity
Fiber optics
gelatins
fiber optics
Optical fibers
optical fibers
Experiments
Lighting
illumination
Solenoids
solenoids
viability
Light sources
light sources
Actuators
Gels
actuators
gels

Keywords

  • Displacement
  • Dynamic viscoelasticity
  • Embryo viability
  • Fiber-optic
  • Gelatin gel model
  • IVF-ET
  • Measurement system
  • Reflectometry

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Itoh, H., Arai, T., Kikuchi, M., Morita, N., & Obara, M. (1998). Embryo viscoelasticity measurement by fiber-optic system: System development and model experiment. In R. A. Lieberman, & T. Vo-Dinh (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 3253, pp. 89-93) https://doi.org/10.1117/12.308019

Embryo viscoelasticity measurement by fiber-optic system : System development and model experiment. / Itoh, Harumi; Arai, Tsunenori; Kikuchi, Makoto; Morita, Naoko; Obara, Minoru.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / R.A. Lieberman; T. Vo-Dinh. Vol. 3253 1998. p. 89-93.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Itoh, H, Arai, T, Kikuchi, M, Morita, N & Obara, M 1998, Embryo viscoelasticity measurement by fiber-optic system: System development and model experiment. in RA Lieberman & T Vo-Dinh (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 3253, pp. 89-93, Biomedical Sensing and Imaging Technologies, San Jose, CA, United States, 98/1/26. https://doi.org/10.1117/12.308019
Itoh H, Arai T, Kikuchi M, Morita N, Obara M. Embryo viscoelasticity measurement by fiber-optic system: System development and model experiment. In Lieberman RA, Vo-Dinh T, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3253. 1998. p. 89-93 https://doi.org/10.1117/12.308019
Itoh, Harumi ; Arai, Tsunenori ; Kikuchi, Makoto ; Morita, Naoko ; Obara, Minoru. / Embryo viscoelasticity measurement by fiber-optic system : System development and model experiment. Proceedings of SPIE - The International Society for Optical Engineering. editor / R.A. Lieberman ; T. Vo-Dinh. Vol. 3253 1998. pp. 89-93
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