Empirical antibiotic usage and bacterial superinfections in patients with COVID-19 in Japan: A nationwide survey by the Japanese Respiratory Society

Takahiro Takazono, Hiroshi Mukae, Koichi Izumikawa, Hiroshi Kakeya, Tadashi Ishida, Naoki Hasegawa, Akihito Yokoyama

Research output: Contribution to journalArticlepeer-review

Abstract

An internet questionnaire survey for investigating empirical antibiotic usage and bacterial superinfections in patients with coronavirus disease-2019 (COVID-19) in Japan was conducted among the chief physicians of respiratory disease departments of 715 Japanese Respiratory Society-certified hospitals using Google Forms between January 28, 2021 and February 28, 2021. Responses to the questionnaire survey were obtained from 198 of 715 hospitals (27.6%). The survey revealed that the complication incidences of community-acquired pneumonia; hospital-acquired pneumonia, including ventilator-associated pneumonia; and sepsis were 2.86, 5.59, and 0.99%, respectively, among patients with moderate/severe and critical COVID-19. Bacterial co-infection and secondary infection rarely affected patients with COVID-19 in Japan, and the isolated pathogens were not specific to these patients. Moreover, the anti-inflammatory effects of macrolides for COVID-19 were not observed in several studies. These results might be useful in clinical practice for COVID-19.

Original languageEnglish
Pages (from-to)154-157
Number of pages4
JournalRespiratory Investigation
Volume60
Issue number1
DOIs
Publication statusPublished - 2022 Jan

Keywords

  • Antibiotic stewardship
  • COVID-19
  • Community-acquired pneumonia
  • Hospital-acquired pneumonia
  • Sepsis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Fingerprint

Dive into the research topics of 'Empirical antibiotic usage and bacterial superinfections in patients with COVID-19 in Japan: A nationwide survey by the Japanese Respiratory Society'. Together they form a unique fingerprint.

Cite this