Enantioselective 1,3-dipolar cycloaddition of nitrones catalyzed by optically active cationic cobalt(III) complexes

Tsuyoshi Mita, Natsuki Ohtsuki, Taketo Ikeno, Tohru Yamada

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(Matrix presented) The optically active β-ketoiminato cationic cobalt(III) complexes were employed as efficient Lewis acid catalysts for the enantioselective 1,3-dipolar cycloaddition reaction of α,β-unsaturated aldehydes with nitrones. Excellent endo selectivities and high enantioselectivities were achieved in the cycloaddition reaction of 1-cyclopentene-1-carbaldehyde and the nitrones derived from 2-halobenzaldehyde.

Original languageEnglish
Pages (from-to)2457-2460
Number of pages4
JournalOrganic Letters
Issue number15
Publication statusPublished - 2002 Jul 25


ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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