Enantioselective 1,3-dipolar cycloaddition of nitrones catalyzed by optically active cationic cobalt(III) complexes

Tsuyoshi Mita, Natsuki Ohtsuki, Taketo Ikeno, Tohru Yamada

Research output: Contribution to journalArticle

90 Citations (Scopus)

Abstract

(Matrix presented) The optically active β-ketoiminato cationic cobalt(III) complexes were employed as efficient Lewis acid catalysts for the enantioselective 1,3-dipolar cycloaddition reaction of α,β-unsaturated aldehydes with nitrones. Excellent endo selectivities and high enantioselectivities were achieved in the cycloaddition reaction of 1-cyclopentene-1-carbaldehyde and the nitrones derived from 2-halobenzaldehyde.

Original languageEnglish
Pages (from-to)2457-2460
Number of pages4
JournalOrganic Letters
Volume4
Issue number15
DOIs
Publication statusPublished - 2002 Jul 25

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Cycloaddition
Cycloaddition Reaction
cycloaddition
Cobalt
cobalt
Cyclopentanes
Lewis Acids
Enantioselectivity
aldehydes
Aldehydes
selectivity
catalysts
acids
Catalysts
matrices
nitrones

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Enantioselective 1,3-dipolar cycloaddition of nitrones catalyzed by optically active cationic cobalt(III) complexes. / Mita, Tsuyoshi; Ohtsuki, Natsuki; Ikeno, Taketo; Yamada, Tohru.

In: Organic Letters, Vol. 4, No. 15, 25.07.2002, p. 2457-2460.

Research output: Contribution to journalArticle

Mita, Tsuyoshi ; Ohtsuki, Natsuki ; Ikeno, Taketo ; Yamada, Tohru. / Enantioselective 1,3-dipolar cycloaddition of nitrones catalyzed by optically active cationic cobalt(III) complexes. In: Organic Letters. 2002 ; Vol. 4, No. 15. pp. 2457-2460.
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