Enantioselective borohydride 1,4-reduction of α,β-unsaturated carboxamides using optically active cobalt(II) complex catalysts

Tohru Yamada, Yuhki Ohtsuka, Taketo Ikeno

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Abstract

The enantioselective borohydride reduction catalyzed by cobalt(II) complex was successfully applied to 1,4-reduction of β,β-disubstituted α,β-unsaturated carboxamides. In the presence of less than 1 mol% of optically active aldiminato cobalt(II) complex catalyst, the corresponding carboxamides were obtained in high yields with high enantiomeric excesses.

Original languageEnglish
Pages (from-to)1129-1130
Number of pages2
JournalChemistry Letters
Issue number11
Publication statusPublished - 1998

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Borohydrides
Cobalt
Catalysts

ASJC Scopus subject areas

  • Chemistry(all)

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Enantioselective borohydride 1,4-reduction of α,β-unsaturated carboxamides using optically active cobalt(II) complex catalysts. / Yamada, Tohru; Ohtsuka, Yuhki; Ikeno, Taketo.

In: Chemistry Letters, No. 11, 1998, p. 1129-1130.

Research output: Contribution to journalArticle

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