Enantioselective borohydride 1,4-reduction of α,β-unsaturated carboxamides using optically active cobalt(II) complex catalysts

Tohru Yamada, Yuhki Ohtsuka, Taketo Ikeno

Research output: Contribution to journalArticlepeer-review

47 Citations (Scopus)

Abstract

The enantioselective borohydride reduction catalyzed by cobalt(II) complex was successfully applied to 1,4-reduction of β,β-disubstituted α,β-unsaturated carboxamides. In the presence of less than 1 mol% of optically active aldiminato cobalt(II) complex catalyst, the corresponding carboxamides were obtained in high yields with high enantiomeric excesses.

Original languageEnglish
Pages (from-to)1129-1130
Number of pages2
JournalChemistry Letters
Issue number11
DOIs
Publication statusPublished - 1998 Jan 1

ASJC Scopus subject areas

  • Chemistry(all)

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