Enantioselective borohydride reduction of N-diphenylphosphinyl imines using optically active cobalt(II) complex catalysts

Kiyoaki D. Sugi, Takushi Nagata, Tohru Yamada, Teruaki Mukaiyama

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Abstract

The enantioselective borohydride reduction using optically active cobalt(II) complex catalysts was successfully applied to various aryl N-diphenylphosphinyl imines, and the corresponding reduced products were obtained in good yields with high enantiomeric excesses (up to 99% ee). The optically active primary amines were obtained by the successive hydrolysis under mild conditions.

Original languageEnglish
Pages (from-to)493-494
Number of pages2
JournalChemistry Letters
Issue number6
Publication statusPublished - 1997
Externally publishedYes

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ASJC Scopus subject areas

  • Chemistry(all)

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