Enantioselective distribution behavior of (±)-pindolol in a liquid- liquid two-phase system containing optically active diol and boric acid

Yoshihiro Abe, Wang Qing, Tomoko Shoji, Shikie Fukui, Mayumi Suzuki, Takako Kamiyama, Michi Kobayashi, Hideyuki Nishizawa

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4 Citations (Scopus)

Abstract

Enantioselective distribution of (±)-pindolol was observed in a chloroform-boric acid two-phase system in the presence of (1R,2R)-(+)- hydrobenzoin,1,4-di-O-dodecyl L-threitol, (R)-(+)- or (S)-(-)-1,1'-2- binaphthol in the organic phase.

Original languageEnglish
Pages (from-to)1250-1251
Number of pages2
JournalChemical and Pharmaceutical Bulletin
Volume44
Issue number6
DOIs
Publication statusPublished - 1996 Jun

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Keywords

  • binaphthol
  • boric acid
  • enantioseparation
  • hydrobenzoin
  • liquid liquid extraction

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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