Enantioselective ene reaction of cyclopentadiene and α,β-enals catalyzed by a diphenylprolinol silyl ether

Hiroaki Gotoh, Ryouhei Masui, Hiroshi Ogino, Mitsuru Shoji, Yujiro Hayashi

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87 Citations (Scopus)


(Chemical Equation Presented) The opposite result: A diphenylprolinol silyl ether promotes an intermolecular enantioselective ene reaction of α,β-enals with cyclopentadiene. This is the first example of cyclopentadiene acting as the ene component, and not the diene, with α,β-enals.

Original languageEnglish
Pages (from-to)6853-6856
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number41
Publication statusPublished - 2006 Oct 20



  • Asymmetric synthesis
  • Cyclopentadiene
  • Diels-Alder reaction
  • Ene reaction
  • Organocatalysis

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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