Enantioselective Synthesis of Aurilide, a Cytotoxic 26-Membered Cyclodepsipeptide of Marine Origin

Tsuyoshi Mutou, Kiyotake Suenaga, Tatsuya Fujita, Takashi Itoh, Noboru Takada, Kozue Hayamizu, Hideo Kigoshi, Kiyoyuki Yamada

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Aurilide (1), a novel cyclodepsipeptide isolated from the Japanese sea hare Dolabella auricularia, was enantioselectively synthesized, and the present result unambiguously confirmed its stereostructure. In addition, the cytotoxicity of 1 was evaluated by employing synthetic 1.

Original languageEnglish
Pages (from-to)199-201
Number of pages3
JournalSynlett
Volume1997
Issue number2
Publication statusPublished - 1997
Externally publishedYes

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Depsipeptides
Cytotoxicity
aurilide

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Mutou, T., Suenaga, K., Fujita, T., Itoh, T., Takada, N., Hayamizu, K., ... Yamada, K. (1997). Enantioselective Synthesis of Aurilide, a Cytotoxic 26-Membered Cyclodepsipeptide of Marine Origin. Synlett, 1997(2), 199-201.

Enantioselective Synthesis of Aurilide, a Cytotoxic 26-Membered Cyclodepsipeptide of Marine Origin. / Mutou, Tsuyoshi; Suenaga, Kiyotake; Fujita, Tatsuya; Itoh, Takashi; Takada, Noboru; Hayamizu, Kozue; Kigoshi, Hideo; Yamada, Kiyoyuki.

In: Synlett, Vol. 1997, No. 2, 1997, p. 199-201.

Research output: Contribution to journalArticle

Mutou, T, Suenaga, K, Fujita, T, Itoh, T, Takada, N, Hayamizu, K, Kigoshi, H & Yamada, K 1997, 'Enantioselective Synthesis of Aurilide, a Cytotoxic 26-Membered Cyclodepsipeptide of Marine Origin', Synlett, vol. 1997, no. 2, pp. 199-201.
Mutou T, Suenaga K, Fujita T, Itoh T, Takada N, Hayamizu K et al. Enantioselective Synthesis of Aurilide, a Cytotoxic 26-Membered Cyclodepsipeptide of Marine Origin. Synlett. 1997;1997(2):199-201.
Mutou, Tsuyoshi ; Suenaga, Kiyotake ; Fujita, Tatsuya ; Itoh, Takashi ; Takada, Noboru ; Hayamizu, Kozue ; Kigoshi, Hideo ; Yamada, Kiyoyuki. / Enantioselective Synthesis of Aurilide, a Cytotoxic 26-Membered Cyclodepsipeptide of Marine Origin. In: Synlett. 1997 ; Vol. 1997, No. 2. pp. 199-201.
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