Enantioselective synthesis of curacin A. 2. Total synthesis of curacin A by condensation of C1-C7, C8-C17, and C18-C22 segments

Hisanaka Ito, Nobuyuki Imai, Kenichi Takao, Susumu Kobayashi

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Total synthesis of curacin A, a novel antimitotic antiproliferative antibiotic, was achieved by the connection of C1-C7, C8-C17, and C18-C22 segments by Julia coupling and iminoether condensation.

Original languageEnglish
Pages (from-to)1799-1800
Number of pages2
JournalTetrahedron Letters
Volume37
Issue number11
DOIs
Publication statusPublished - 1996 Mar 11
Externally publishedYes

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Antimitotic Agents
Condensation
Anti-Bacterial Agents
curacin A

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Enantioselective synthesis of curacin A. 2. Total synthesis of curacin A by condensation of C1-C7, C8-C17, and C18-C22 segments. / Ito, Hisanaka; Imai, Nobuyuki; Takao, Kenichi; Kobayashi, Susumu.

In: Tetrahedron Letters, Vol. 37, No. 11, 11.03.1996, p. 1799-1800.

Research output: Contribution to journalArticle

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