Enantioselective synthesis of curacin A. 2. Total synthesis of curacin A by condensation of C1-C7, C8-C17, and C18-C22 segments

Hisanaka Ito; Nobuyuki Imai; Ken Ichi Takao; Susumu Kobayashi

doi:10.1016/0040-4039(96)00031-7

Enantioselective synthesis of curacin A. 2. Total synthesis of curacin A by condensation of C1-C7, C8-C17, and C18-C22 segments

Hisanaka Ito, Nobuyuki Imai, Ken Ichi Takao, Susumu Kobayashi

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

Total synthesis of curacin A, a novel antimitotic antiproliferative antibiotic, was achieved by the connection of C1-C7, C8-C17, and C18-C22 segments by Julia coupling and iminoether condensation.

Original language	English
Pages (from-to)	1799-1800
Number of pages	2
Journal	Tetrahedron Letters
Volume	37
Issue number	11
DOIs	https://doi.org/10.1016/0040-4039(96)00031-7
Publication status	Published - 1996 Mar 11
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/0040-4039(96)00031-7

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title = "Enantioselective synthesis of curacin A. 2. Total synthesis of curacin A by condensation of C1-C7, C8-C17, and C18-C22 segments",

abstract = "Total synthesis of curacin A, a novel antimitotic antiproliferative antibiotic, was achieved by the connection of C1-C7, C8-C17, and C18-C22 segments by Julia coupling and iminoether condensation.",

author = "Hisanaka Ito and Nobuyuki Imai and Takao, {Ken Ichi} and Susumu Kobayashi",

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AU - Ito, Hisanaka

AU - Imai, Nobuyuki

AU - Takao, Ken Ichi

AU - Kobayashi, Susumu

PY - 1996/3/11

Y1 - 1996/3/11

N2 - Total synthesis of curacin A, a novel antimitotic antiproliferative antibiotic, was achieved by the connection of C1-C7, C8-C17, and C18-C22 segments by Julia coupling and iminoether condensation.

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Enantioselective synthesis of curacin A. 2. Total synthesis of curacin A by condensation of C1-C7, C8-C17, and C18-C22 segments

Abstract

ASJC Scopus subject areas

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