Enantiospecific syntheses of (+)- and (-)-altholactone (goniothalenol)

John G. Gillhouley; Tony K.M. Shing

doi:10.1039/C39880000976

Enantiospecific syntheses of (+)- and (-)-altholactone (goniothalenol)

John G. Gillhouley, Tony K.M. Shing

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

(+)-Altholactone (1) and its enantiomer (2) have been synthesised from D-gulonolactone and D-mannose, respectively, with stereocontrolled reduction (Et₃SiH/BF₃·Et₂O) of the lactols (4) and (10) as a key step.

Original language	English
Pages (from-to)	976-977
Number of pages	2
Journal	Journal of the Chemical Society, Chemical Communications
Issue number	14
DOIs	https://doi.org/10.1039/C39880000976
Publication status	Published - 1988 Jan 1

ASJC Scopus subject areas

Molecular Medicine

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title = "Enantiospecific syntheses of (+)- and (-)-altholactone (goniothalenol)",

abstract = "(+)-Altholactone (1) and its enantiomer (2) have been synthesised from D-gulonolactone and D-mannose, respectively, with stereocontrolled reduction (Et3SiH/BF3·Et2O) of the lactols (4) and (10) as a key step.",

author = "Gillhouley, {John G.} and Shing, {Tony K.M.}",

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AU - Shing, Tony K.M.

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N2 - (+)-Altholactone (1) and its enantiomer (2) have been synthesised from D-gulonolactone and D-mannose, respectively, with stereocontrolled reduction (Et3SiH/BF3·Et2O) of the lactols (4) and (10) as a key step.

AB - (+)-Altholactone (1) and its enantiomer (2) have been synthesised from D-gulonolactone and D-mannose, respectively, with stereocontrolled reduction (Et3SiH/BF3·Et2O) of the lactols (4) and (10) as a key step.

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JO - Chemical Communications

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IS - 14

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Enantiospecific syntheses of (+)- and (-)-altholactone (goniothalenol)

Abstract

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