Enantiospecific synthesis of 2-crotonyloxy-(4R,5R,6R)-4,5,6- trihydroxycyclohex-2-enone (COTC) from quinic acid

Tony K.M. Shing, Ying Tang

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

A thirteen-step synthesis of the glyoxalase I inhibitor COTC [2-Crotonyloxy-(4R,5R,6R)-4,5,6-trihydroxycyclohex-2-enone] from quinic acid is described.

Original languageEnglish
Number of pages1
JournalJournal of the Chemical Society, Chemical Communications
Issue number4
DOIs
Publication statusPublished - 1990 Dec 1

ASJC Scopus subject areas

  • Molecular Medicine

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