Enantiospecific synthesis of C20C28 segment of concanamycin A: Application of diethylisopropylsilyl protecting group

Kazunobu Toshima, Mari Misawa, Kazumi Ohta, Kuniaki Tatsuta, Mitsuhiro Kinoshita

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

A complex C20C28 segment 5 of concanamycin A (1) has been first synthesized without side reactions by effective de-O-silylation of 2a, which was constructed from the ethyl ketone 3 by glycosidation with the fluoride 4.

Original languageEnglish
Pages (from-to)6417-6420
Number of pages4
JournalTetrahedron Letters
Volume30
Issue number46
DOIs
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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