Abstract
Total synthesis of (-)-allosamizoline (2), an aminocyclitol moiety of the insect chitinase inhibitor allosamidin (1) has been enantiospecifically synthesized from D-glucosamine by using an intramolecular cycloaddition of the nitrile oxide to an olefin as a key step.
Original language | English |
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Pages (from-to) | 5363-5366 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 32 |
Issue number | 39 |
DOIs | |
Publication status | Published - 1991 Sep 23 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry