Abstract
Total synthesis of (-)-allosamizoline (2), an aminocyclitol moiety of the insect chitinase inhibitor allosamidin (1) has been enantiospecifically synthesized from D-glucosamine by using an intramolecular cycloaddition of the nitrile oxide to an olefin as a key step.
| Original language | English |
|---|---|
| Pages (from-to) | 5363-5366 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 32 |
| Issue number | 39 |
| DOIs | |
| Publication status | Published - 1991 Sep 23 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
Fingerprint Dive into the research topics of 'Enantiospecific total synthesis of (-)-allosamizoline, and aminocyclitol moiety of the insect chitinase inhibitor allosamidin'. Together they form a unique fingerprint.
Cite this
Nakata, M., Akazawa, S., Kitamura, S., & Tatsuta, K. (1991). Enantiospecific total synthesis of (-)-allosamizoline, and aminocyclitol moiety of the insect chitinase inhibitor allosamidin. Tetrahedron Letters, 32(39), 5363-5366. https://doi.org/10.1016/S0040-4039(00)92386-4