Endocytoscopy

Novel endoscopic imaging technology for in-situ observation of bladder cancer cells

Takashi Ohigashi, Norihide Kozakai, Ryuichi Mizuno, Akira Miyajima, Masaru Murai

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Background and Purpose: Recent advances in endoscopy have enabled microscopic imaging of live bladder-cancer cells in situ. The newly developed Endocystoscopy system (Olympus Medical Systems Co., Tokyo, Japan) is a flexible digital endoscope that has more than a 450-fold magnifying power on a video monitor. Patients and Methods: This supermagnifying endoscope was used to evaluate bladder carcinoma in five patients through the working channel of a rigid cystoscope. Results: The cell structure and nuclear morphology were imaged adequately compared with conventional hematoxylin and eosin staining of a biopsy specimen. The tumors were graded correctly in four of five cases. Conclusion: This novel technology appears to be useful for histologic diagnosis during endoscopic examinations, potentially allowing us to avoid a conventional biopsy.

Original languageEnglish
Pages (from-to)698-701
Number of pages4
JournalJournal of Endourology
Volume20
Issue number9
DOIs
Publication statusPublished - 2006 Sep

Fingerprint

Endoscopes
Urinary Bladder Neoplasms
Cystoscopes
Observation
Technology
Biopsy
Tokyo
Hematoxylin
Eosine Yellowish-(YS)
Endoscopy
Japan
Urinary Bladder
Staining and Labeling
Carcinoma
Neoplasms

ASJC Scopus subject areas

  • Urology

Cite this

Endocytoscopy : Novel endoscopic imaging technology for in-situ observation of bladder cancer cells. / Ohigashi, Takashi; Kozakai, Norihide; Mizuno, Ryuichi; Miyajima, Akira; Murai, Masaru.

In: Journal of Endourology, Vol. 20, No. 9, 09.2006, p. 698-701.

Research output: Contribution to journalArticle

Ohigashi, Takashi ; Kozakai, Norihide ; Mizuno, Ryuichi ; Miyajima, Akira ; Murai, Masaru. / Endocytoscopy : Novel endoscopic imaging technology for in-situ observation of bladder cancer cells. In: Journal of Endourology. 2006 ; Vol. 20, No. 9. pp. 698-701.
@article{0d61a78c9a754dc1b7bdf8cc348f6122,
title = "Endocytoscopy: Novel endoscopic imaging technology for in-situ observation of bladder cancer cells",
abstract = "Background and Purpose: Recent advances in endoscopy have enabled microscopic imaging of live bladder-cancer cells in situ. The newly developed Endocystoscopy system (Olympus Medical Systems Co., Tokyo, Japan) is a flexible digital endoscope that has more than a 450-fold magnifying power on a video monitor. Patients and Methods: This supermagnifying endoscope was used to evaluate bladder carcinoma in five patients through the working channel of a rigid cystoscope. Results: The cell structure and nuclear morphology were imaged adequately compared with conventional hematoxylin and eosin staining of a biopsy specimen. The tumors were graded correctly in four of five cases. Conclusion: This novel technology appears to be useful for histologic diagnosis during endoscopic examinations, potentially allowing us to avoid a conventional biopsy.",
author = "Takashi Ohigashi and Norihide Kozakai and Ryuichi Mizuno and Akira Miyajima and Masaru Murai",
year = "2006",
month = "9",
doi = "10.1089/end.2006.20.698",
language = "English",
volume = "20",
pages = "698--701",
journal = "Journal of Endourology",
issn = "0892-7790",
publisher = "Mary Ann Liebert Inc.",
number = "9",

}

TY - JOUR

T1 - Endocytoscopy

T2 - Novel endoscopic imaging technology for in-situ observation of bladder cancer cells

AU - Ohigashi, Takashi

AU - Kozakai, Norihide

AU - Mizuno, Ryuichi

AU - Miyajima, Akira

AU - Murai, Masaru

PY - 2006/9

Y1 - 2006/9

N2 - Background and Purpose: Recent advances in endoscopy have enabled microscopic imaging of live bladder-cancer cells in situ. The newly developed Endocystoscopy system (Olympus Medical Systems Co., Tokyo, Japan) is a flexible digital endoscope that has more than a 450-fold magnifying power on a video monitor. Patients and Methods: This supermagnifying endoscope was used to evaluate bladder carcinoma in five patients through the working channel of a rigid cystoscope. Results: The cell structure and nuclear morphology were imaged adequately compared with conventional hematoxylin and eosin staining of a biopsy specimen. The tumors were graded correctly in four of five cases. Conclusion: This novel technology appears to be useful for histologic diagnosis during endoscopic examinations, potentially allowing us to avoid a conventional biopsy.

AB - Background and Purpose: Recent advances in endoscopy have enabled microscopic imaging of live bladder-cancer cells in situ. The newly developed Endocystoscopy system (Olympus Medical Systems Co., Tokyo, Japan) is a flexible digital endoscope that has more than a 450-fold magnifying power on a video monitor. Patients and Methods: This supermagnifying endoscope was used to evaluate bladder carcinoma in five patients through the working channel of a rigid cystoscope. Results: The cell structure and nuclear morphology were imaged adequately compared with conventional hematoxylin and eosin staining of a biopsy specimen. The tumors were graded correctly in four of five cases. Conclusion: This novel technology appears to be useful for histologic diagnosis during endoscopic examinations, potentially allowing us to avoid a conventional biopsy.

UR - http://www.scopus.com/inward/record.url?scp=33846463413&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846463413&partnerID=8YFLogxK

U2 - 10.1089/end.2006.20.698

DO - 10.1089/end.2006.20.698

M3 - Article

VL - 20

SP - 698

EP - 701

JO - Journal of Endourology

JF - Journal of Endourology

SN - 0892-7790

IS - 9

ER -