Endometrial stem/progenitor cells

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Human endometrium regenerates and regresses with each menstrual cycle under hormonal control throughout a woman's reproductive life. The cyclical regeneration and remodeling potentials allude to the existence of stem/progenitor cells in the endometrium. There is increasing evidence that human endometrium contains small numbers of stem-like cells capable of self-renewal, multiple differentiation and tissue reconstitution. Although the precise identity of endometrial stem/progenitor cells remains elusive, these cells are thought to play pivotal role(s) in the physiological remodeling and regeneration of the human endometrium and also in the pathogenesis of endometrium-associated diseases, such as endometriosis.

Original languageEnglish
Pages (from-to)2015-2022
Number of pages8
JournalJournal of Obstetrics and Gynaecology Research
Volume40
Issue number9
DOIs
Publication statusPublished - 2014 Sep

Keywords

  • endometrial regeneration
  • endometriosis
  • side population
  • stem/progenitor cells

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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