Abstract
Esophageal achalasia is often associated with esophageal cancer. However, in many cases, esophageal cancer tends to be found in an advanced stage, with a poor prognosis. However, early-stage cancer was detected recently due to the advances in endoscopic instruments. In those cases, it is important to facilitate successful treatment by endoscopic submucosal dissection. We analyzed a total of six cases of esophageal cancer with achalasia in four patients treated with endoscopic submucosal dissection. Three features common to all six cases had a bearing on how endoscopic submucosal dissection was performed. First, esophageal dilatation and diminished peristalsis facilitated the performance of successful endoscopic submucosal dissection. Second, the esophageal wall was thickened, primarily with muscular tissue. Third, the submucosal layer contained abundant blood vessels that made it difficult to minimize bleeding during dissection. Those findings suggest that endoscopic submucosal dissection for early esophageal cancer associated with achalasia is a safe and potentially curative procedure. It is important, therefore, to detect esophageal cancer early.
| Original language | English |
|---|---|
| Pages (from-to) | 161-166 |
| Number of pages | 6 |
| Journal | Turkish Journal of Gastroenterology |
| Volume | 24 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2013 |
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Keywords
- Achalasia
- Endoscopic submucosal dissection
- Esophageal cancer
ASJC Scopus subject areas
- Gastroenterology
Cite this
Endoscopic submucosal dissection for early esophageal cancer associated with achalasia. / Ohkura, Yu; Iizuka, Toshiro; Kikuchi, Daisuke; Yamashita, Satoshi; Nakamura, Masanori; Matsui, Akira; Mitani, Toshifumi; Hoteya, Shu; Kaise, Mitsuru; Yahagi, Naohisa.
In: Turkish Journal of Gastroenterology, Vol. 24, No. 2, 2013, p. 161-166.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Endoscopic submucosal dissection for early esophageal cancer associated with achalasia
AU - Ohkura, Yu
AU - Iizuka, Toshiro
AU - Kikuchi, Daisuke
AU - Yamashita, Satoshi
AU - Nakamura, Masanori
AU - Matsui, Akira
AU - Mitani, Toshifumi
AU - Hoteya, Shu
AU - Kaise, Mitsuru
AU - Yahagi, Naohisa
PY - 2013
Y1 - 2013
N2 - Esophageal achalasia is often associated with esophageal cancer. However, in many cases, esophageal cancer tends to be found in an advanced stage, with a poor prognosis. However, early-stage cancer was detected recently due to the advances in endoscopic instruments. In those cases, it is important to facilitate successful treatment by endoscopic submucosal dissection. We analyzed a total of six cases of esophageal cancer with achalasia in four patients treated with endoscopic submucosal dissection. Three features common to all six cases had a bearing on how endoscopic submucosal dissection was performed. First, esophageal dilatation and diminished peristalsis facilitated the performance of successful endoscopic submucosal dissection. Second, the esophageal wall was thickened, primarily with muscular tissue. Third, the submucosal layer contained abundant blood vessels that made it difficult to minimize bleeding during dissection. Those findings suggest that endoscopic submucosal dissection for early esophageal cancer associated with achalasia is a safe and potentially curative procedure. It is important, therefore, to detect esophageal cancer early.
AB - Esophageal achalasia is often associated with esophageal cancer. However, in many cases, esophageal cancer tends to be found in an advanced stage, with a poor prognosis. However, early-stage cancer was detected recently due to the advances in endoscopic instruments. In those cases, it is important to facilitate successful treatment by endoscopic submucosal dissection. We analyzed a total of six cases of esophageal cancer with achalasia in four patients treated with endoscopic submucosal dissection. Three features common to all six cases had a bearing on how endoscopic submucosal dissection was performed. First, esophageal dilatation and diminished peristalsis facilitated the performance of successful endoscopic submucosal dissection. Second, the esophageal wall was thickened, primarily with muscular tissue. Third, the submucosal layer contained abundant blood vessels that made it difficult to minimize bleeding during dissection. Those findings suggest that endoscopic submucosal dissection for early esophageal cancer associated with achalasia is a safe and potentially curative procedure. It is important, therefore, to detect esophageal cancer early.
KW - Achalasia
KW - Endoscopic submucosal dissection
KW - Esophageal cancer
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UR - http://www.scopus.com/inward/citedby.url?scp=84880880736&partnerID=8YFLogxK
U2 - 10.4318/tjg.2013.0522
DO - 10.4318/tjg.2013.0522
M3 - Article
VL - 24
SP - 161
EP - 166
JO - Turkish Journal of Gastroenterology
JF - Turkish Journal of Gastroenterology
SN - 1300-4948
IS - 2
ER -