Endoscopic submucosal dissection for the reliable en bloc resection of colorectal mucosal tumors

Naohisa Yahagi, Mitsuhiro Fujishiro, Atsushi Imagawa, Naomi Kakushima, Mikitaka Iguchi, Masao Omata

Research output: Contribution to journalArticlepeer-review

86 Citations (Scopus)


Scheduled piecemeal resection has been actively conducted for granular type laterally spreading tumor (LST-G) in Japan, as long as a definite preoperative diagnosis is made. However, en bloc resection is desirable for depressed lesions (e.g. Ilc lesion) as well as non-granular type laterally spreading tumor (LST-NG) since they have considerable high risk for submucoasl invasion and require precise histopathological evaluation. Endoscopic submucosal dissection (ESD) has been developed for the en bloc resection of mucosal tumors of gastrointestinal tract and widely applied especially in gastric lesions. Although the large intestine involves structural and technical difficulties, we conducted en bloc resection by ESD while exercising sorts of ingenuity for preparation; endoscopes, instruments, local injections, and others. ESD is a reliable technique that allows en bloc resection of gastrointestinal mucosal lesions, and even has a splendid possibility for the treatment of early stage colorectal cancer.

Original languageEnglish
Pages (from-to)S89-S92
JournalDigestive Endoscopy
Issue numberSUPPL.
Publication statusPublished - 2004
Externally publishedYes


  • Colorectal mucosal tumor
  • En bloc resection
  • Endoscopic submucosal dissection (ESD)
  • Flex knife
  • LST-NG

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology


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