Endoscopic submucosal dissection of stomach neoplasms after unsuccessful endoscopic resection

M. Fujishiro, O. Goto, N. Kakushima, S. Kodashima, Y. Muraki, M. Omata

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Background: Endoscopic submucosal dissection is a novel endoluminal endoscopic surgery that enables resection of pre-malignant and early-stage malignant gastrointestinal neoplasms in an en bloc fashion. Aim: To assess the feasibility of endoscopic submucosal dissection of stomach neoplasms with submucosal fibrosis caused by unsuccessful endoscopic resection. Patients and methods: Stomach endoscopic submucosal dissection was performed in ten consecutive patients who had unsuccessful endoscopic tumour resection at another hospital between 2003 and 2006. Seven patients had recurrent tumours after complete endoscopic resection, and three patients had incomplete resections due to complications or technical difficulties. Technical feasibility and follow-up data were collected from the patients' reports. Results: All tumours were resected by endoscopic submucosal dissection in one piece without complications. R0 resection (en bloc resection with tumour-free margins) was achieved in nine patients (90%). One patient received additional surgery (gastrectomy) because of submucosal deep invasion with vascular infiltration of the cancer. All patients, including the patient with gastrectomy, have survived without recurrence during a mean follow-up period of 21.4 months (range 3-36 months). Conclusions: Endoscopic submucosal dissection is an effective and safe method for resection of stomach neoplasms after unsuccessful endoscopic resection.

Original languageEnglish
Pages (from-to)566-571
Number of pages6
JournalDigestive and Liver Disease
Volume39
Issue number6
DOIs
Publication statusPublished - 2007 Jun
Externally publishedYes

Fingerprint

Stomach Neoplasms
Gastrectomy
Neoplasms
Endoscopic Mucosal Resection
Gastrointestinal Neoplasms
Blood Vessels
Stomach
Fibrosis
Recurrence

Keywords

  • Endoscopic submucosal dissection
  • Local recurrence
  • Residual tumour
  • Stomach neoplasm
  • Submucosal fibrosis

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Endoscopic submucosal dissection of stomach neoplasms after unsuccessful endoscopic resection. / Fujishiro, M.; Goto, O.; Kakushima, N.; Kodashima, S.; Muraki, Y.; Omata, M.

In: Digestive and Liver Disease, Vol. 39, No. 6, 06.2007, p. 566-571.

Research output: Contribution to journalArticle

Fujishiro, M, Goto, O, Kakushima, N, Kodashima, S, Muraki, Y & Omata, M 2007, 'Endoscopic submucosal dissection of stomach neoplasms after unsuccessful endoscopic resection', Digestive and Liver Disease, vol. 39, no. 6, pp. 566-571. https://doi.org/10.1016/j.dld.2007.01.026
Fujishiro, M. ; Goto, O. ; Kakushima, N. ; Kodashima, S. ; Muraki, Y. ; Omata, M. / Endoscopic submucosal dissection of stomach neoplasms after unsuccessful endoscopic resection. In: Digestive and Liver Disease. 2007 ; Vol. 39, No. 6. pp. 566-571.
@article{2551abd528794639add7883ea825652f,
title = "Endoscopic submucosal dissection of stomach neoplasms after unsuccessful endoscopic resection",
abstract = "Background: Endoscopic submucosal dissection is a novel endoluminal endoscopic surgery that enables resection of pre-malignant and early-stage malignant gastrointestinal neoplasms in an en bloc fashion. Aim: To assess the feasibility of endoscopic submucosal dissection of stomach neoplasms with submucosal fibrosis caused by unsuccessful endoscopic resection. Patients and methods: Stomach endoscopic submucosal dissection was performed in ten consecutive patients who had unsuccessful endoscopic tumour resection at another hospital between 2003 and 2006. Seven patients had recurrent tumours after complete endoscopic resection, and three patients had incomplete resections due to complications or technical difficulties. Technical feasibility and follow-up data were collected from the patients' reports. Results: All tumours were resected by endoscopic submucosal dissection in one piece without complications. R0 resection (en bloc resection with tumour-free margins) was achieved in nine patients (90{\%}). One patient received additional surgery (gastrectomy) because of submucosal deep invasion with vascular infiltration of the cancer. All patients, including the patient with gastrectomy, have survived without recurrence during a mean follow-up period of 21.4 months (range 3-36 months). Conclusions: Endoscopic submucosal dissection is an effective and safe method for resection of stomach neoplasms after unsuccessful endoscopic resection.",
keywords = "Endoscopic submucosal dissection, Local recurrence, Residual tumour, Stomach neoplasm, Submucosal fibrosis",
author = "M. Fujishiro and O. Goto and N. Kakushima and S. Kodashima and Y. Muraki and M. Omata",
year = "2007",
month = "6",
doi = "10.1016/j.dld.2007.01.026",
language = "English",
volume = "39",
pages = "566--571",
journal = "Digestive and Liver Disease",
issn = "1590-8658",
publisher = "Elsevier",
number = "6",

}

TY - JOUR

T1 - Endoscopic submucosal dissection of stomach neoplasms after unsuccessful endoscopic resection

AU - Fujishiro, M.

AU - Goto, O.

AU - Kakushima, N.

AU - Kodashima, S.

AU - Muraki, Y.

AU - Omata, M.

PY - 2007/6

Y1 - 2007/6

N2 - Background: Endoscopic submucosal dissection is a novel endoluminal endoscopic surgery that enables resection of pre-malignant and early-stage malignant gastrointestinal neoplasms in an en bloc fashion. Aim: To assess the feasibility of endoscopic submucosal dissection of stomach neoplasms with submucosal fibrosis caused by unsuccessful endoscopic resection. Patients and methods: Stomach endoscopic submucosal dissection was performed in ten consecutive patients who had unsuccessful endoscopic tumour resection at another hospital between 2003 and 2006. Seven patients had recurrent tumours after complete endoscopic resection, and three patients had incomplete resections due to complications or technical difficulties. Technical feasibility and follow-up data were collected from the patients' reports. Results: All tumours were resected by endoscopic submucosal dissection in one piece without complications. R0 resection (en bloc resection with tumour-free margins) was achieved in nine patients (90%). One patient received additional surgery (gastrectomy) because of submucosal deep invasion with vascular infiltration of the cancer. All patients, including the patient with gastrectomy, have survived without recurrence during a mean follow-up period of 21.4 months (range 3-36 months). Conclusions: Endoscopic submucosal dissection is an effective and safe method for resection of stomach neoplasms after unsuccessful endoscopic resection.

AB - Background: Endoscopic submucosal dissection is a novel endoluminal endoscopic surgery that enables resection of pre-malignant and early-stage malignant gastrointestinal neoplasms in an en bloc fashion. Aim: To assess the feasibility of endoscopic submucosal dissection of stomach neoplasms with submucosal fibrosis caused by unsuccessful endoscopic resection. Patients and methods: Stomach endoscopic submucosal dissection was performed in ten consecutive patients who had unsuccessful endoscopic tumour resection at another hospital between 2003 and 2006. Seven patients had recurrent tumours after complete endoscopic resection, and three patients had incomplete resections due to complications or technical difficulties. Technical feasibility and follow-up data were collected from the patients' reports. Results: All tumours were resected by endoscopic submucosal dissection in one piece without complications. R0 resection (en bloc resection with tumour-free margins) was achieved in nine patients (90%). One patient received additional surgery (gastrectomy) because of submucosal deep invasion with vascular infiltration of the cancer. All patients, including the patient with gastrectomy, have survived without recurrence during a mean follow-up period of 21.4 months (range 3-36 months). Conclusions: Endoscopic submucosal dissection is an effective and safe method for resection of stomach neoplasms after unsuccessful endoscopic resection.

KW - Endoscopic submucosal dissection

KW - Local recurrence

KW - Residual tumour

KW - Stomach neoplasm

KW - Submucosal fibrosis

UR - http://www.scopus.com/inward/record.url?scp=34248563408&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34248563408&partnerID=8YFLogxK

U2 - 10.1016/j.dld.2007.01.026

DO - 10.1016/j.dld.2007.01.026

M3 - Article

C2 - 17382610

AN - SCOPUS:34248563408

VL - 39

SP - 566

EP - 571

JO - Digestive and Liver Disease

JF - Digestive and Liver Disease

SN - 1590-8658

IS - 6

ER -