Endoscopic therapy for gastroesophageal reflux disease

Hidekazu Suzuki, Eisuke Iwasaki, Toshifumi Hibi

Research output: Contribution to journalArticle

Abstract

A variety of endoscopic techniques for the treatment of gastroesophageal reflux disease (GERD) have been developed as alternatives to PPI therapy or antireflux surgery. These techniques include the delivery of radiofrequency energy to the gastroesophageal junction, injection of agents into the lower esophageal sphincter zone, and suture plication of the proximal fundic folds. Each of these endoscopic techniques is designed to alter the anatomy or physiology of the gastroesophageal junction to decrease gastroesophageal reflux. However, only limited data are available on the mechanism of action of the various endoscopic techniques. Most studies of endoscopic therapy have only limited follow-up information, and safety issues remain unresolved. Further sham-controlled clinical trials will be required for endoscopic device and technique.

Original languageEnglish
Pages (from-to)895-899
Number of pages5
JournalNippon rinsho. Japanese journal of clinical medicine
Volume65
Issue number5
Publication statusPublished - 2007 May

Fingerprint

Gastroesophageal Reflux
Esophagogastric Junction
Lower Esophageal Sphincter
Controlled Clinical Trials
Sutures
Anatomy
Therapeutics
Safety
Equipment and Supplies
Injections

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Endoscopic therapy for gastroesophageal reflux disease. / Suzuki, Hidekazu; Iwasaki, Eisuke; Hibi, Toshifumi.

In: Nippon rinsho. Japanese journal of clinical medicine, Vol. 65, No. 5, 05.2007, p. 895-899.

Research output: Contribution to journalArticle

@article{586db5f6e8884ee5b082f049ed5ced66,
title = "Endoscopic therapy for gastroesophageal reflux disease",
abstract = "A variety of endoscopic techniques for the treatment of gastroesophageal reflux disease (GERD) have been developed as alternatives to PPI therapy or antireflux surgery. These techniques include the delivery of radiofrequency energy to the gastroesophageal junction, injection of agents into the lower esophageal sphincter zone, and suture plication of the proximal fundic folds. Each of these endoscopic techniques is designed to alter the anatomy or physiology of the gastroesophageal junction to decrease gastroesophageal reflux. However, only limited data are available on the mechanism of action of the various endoscopic techniques. Most studies of endoscopic therapy have only limited follow-up information, and safety issues remain unresolved. Further sham-controlled clinical trials will be required for endoscopic device and technique.",
author = "Hidekazu Suzuki and Eisuke Iwasaki and Toshifumi Hibi",
year = "2007",
month = "5",
language = "English",
volume = "65",
pages = "895--899",
journal = "Nihon rinsho. Japanese journal of clinical medicine",
issn = "0047-1852",
publisher = "Nipponrinsho Co., Inc.",
number = "5",

}

TY - JOUR

T1 - Endoscopic therapy for gastroesophageal reflux disease

AU - Suzuki, Hidekazu

AU - Iwasaki, Eisuke

AU - Hibi, Toshifumi

PY - 2007/5

Y1 - 2007/5

N2 - A variety of endoscopic techniques for the treatment of gastroesophageal reflux disease (GERD) have been developed as alternatives to PPI therapy or antireflux surgery. These techniques include the delivery of radiofrequency energy to the gastroesophageal junction, injection of agents into the lower esophageal sphincter zone, and suture plication of the proximal fundic folds. Each of these endoscopic techniques is designed to alter the anatomy or physiology of the gastroesophageal junction to decrease gastroesophageal reflux. However, only limited data are available on the mechanism of action of the various endoscopic techniques. Most studies of endoscopic therapy have only limited follow-up information, and safety issues remain unresolved. Further sham-controlled clinical trials will be required for endoscopic device and technique.

AB - A variety of endoscopic techniques for the treatment of gastroesophageal reflux disease (GERD) have been developed as alternatives to PPI therapy or antireflux surgery. These techniques include the delivery of radiofrequency energy to the gastroesophageal junction, injection of agents into the lower esophageal sphincter zone, and suture plication of the proximal fundic folds. Each of these endoscopic techniques is designed to alter the anatomy or physiology of the gastroesophageal junction to decrease gastroesophageal reflux. However, only limited data are available on the mechanism of action of the various endoscopic techniques. Most studies of endoscopic therapy have only limited follow-up information, and safety issues remain unresolved. Further sham-controlled clinical trials will be required for endoscopic device and technique.

UR - http://www.scopus.com/inward/record.url?scp=34447558233&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34447558233&partnerID=8YFLogxK

M3 - Article

C2 - 17511230

AN - SCOPUS:34447558233

VL - 65

SP - 895

EP - 899

JO - Nihon rinsho. Japanese journal of clinical medicine

JF - Nihon rinsho. Japanese journal of clinical medicine

SN - 0047-1852

IS - 5

ER -