Enhanced electrochemical response in oxidative differential pulse voltammetry of dopamine in the presence of ascorbic acid at carboxyl-terminated boron-doped diamond electrodes

Takeshi Kondo; Yu Niwano; Akira Tamura; Junichi Imai; Kensuke Honda; Yasuaki Einaga; Donald A. Tryk; Akira Fujishima; Takeshi Kawai

doi:10.1016/j.electacta.2008.10.073

Enhanced electrochemical response in oxidative differential pulse voltammetry of dopamine in the presence of ascorbic acid at carboxyl-terminated boron-doped diamond electrodes

Takeshi Kondo, Yu Niwano, Akira Tamura, Junichi Imai, Kensuke Honda, Yasuaki Einaga, Donald A. Tryk, Akira Fujishima, Takeshi Kawai

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

45 Citations (Scopus)

Abstract

The differential pulse voltammetric (DPV) peak for dopamine (DA) oxidation was found to be highly amplified by the addition of ascorbic acid (AA) when carboxyl-terminated boron-doped diamond (BDD) electrodes were used as the working electrode. The DP voltammogram for a solution containing DA and AA obtained using a 4-pentenoic acid-modified BDD (4PA-BDD) electrode showed well-separated oxidation peaks for DA and AA at 0.4 and 0.6 V vs. Ag/AgCl, respectively. In addition, as the DA concentration increased at constant AA concentration, a simultaneous increase in the DA peak current density and decrease in the AA peak current density were observed. The slope of the calibration curve for the [DA] range of 1-10 μM in the presence of AA (500 μM) was seven times larger than that obtained in the absence of AA. Such an enhancement was found to be more efficient at 4PA-BDD than at oxidized-BDD, partly due to simple electrostatic effects and partly due to suppression of the polymerization of DA oxidation products by the terminal carboxyl groups. The enhanced detection method using a carboxyl-terminated BDD electrode should be an effective analytical tool, especially for determining low concentrations of DA in the presence of high concentrations of AA.

Original language	English
Pages (from-to)	2312-2319
Number of pages	8
Journal	Electrochimica Acta
Volume	54
Issue number	8
DOIs	https://doi.org/10.1016/j.electacta.2008.10.073
Publication status	Published - 2009 Mar 1

Keywords

Boron-doped diamond
Carboxyl-terminated surface
Differential pulse voltammetry
Dopamine
Electrochemical amplification

ASJC Scopus subject areas

Chemical Engineering(all)
Electrochemistry

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10.1016/j.electacta.2008.10.073

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Kondo, T., Niwano, Y., Tamura, A., Imai, J., Honda, K., Einaga, Y., Tryk, D. A., Fujishima, A., & Kawai, T. (2009). Enhanced electrochemical response in oxidative differential pulse voltammetry of dopamine in the presence of ascorbic acid at carboxyl-terminated boron-doped diamond electrodes. Electrochimica Acta, 54(8), 2312-2319. https://doi.org/10.1016/j.electacta.2008.10.073

Enhanced electrochemical response in oxidative differential pulse voltammetry of dopamine in the presence of ascorbic acid at carboxyl-terminated boron-doped diamond electrodes. / Kondo, Takeshi; Niwano, Yu; Tamura, Akira; Imai, Junichi; Honda, Kensuke; Einaga, Yasuaki; Tryk, Donald A.; Fujishima, Akira; Kawai, Takeshi.

In: Electrochimica Acta, Vol. 54, No. 8, 01.03.2009, p. 2312-2319.

Research output: Contribution to journal › Article › peer-review

Kondo, T, Niwano, Y, Tamura, A, Imai, J, Honda, K, Einaga, Y, Tryk, DA, Fujishima, A & Kawai, T 2009, 'Enhanced electrochemical response in oxidative differential pulse voltammetry of dopamine in the presence of ascorbic acid at carboxyl-terminated boron-doped diamond electrodes', Electrochimica Acta, vol. 54, no. 8, pp. 2312-2319. https://doi.org/10.1016/j.electacta.2008.10.073

Kondo, Takeshi ; Niwano, Yu ; Tamura, Akira ; Imai, Junichi ; Honda, Kensuke ; Einaga, Yasuaki ; Tryk, Donald A. ; Fujishima, Akira ; Kawai, Takeshi. / Enhanced electrochemical response in oxidative differential pulse voltammetry of dopamine in the presence of ascorbic acid at carboxyl-terminated boron-doped diamond electrodes. In: Electrochimica Acta. 2009 ; Vol. 54, No. 8. pp. 2312-2319.

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title = "Enhanced electrochemical response in oxidative differential pulse voltammetry of dopamine in the presence of ascorbic acid at carboxyl-terminated boron-doped diamond electrodes",

abstract = "The differential pulse voltammetric (DPV) peak for dopamine (DA) oxidation was found to be highly amplified by the addition of ascorbic acid (AA) when carboxyl-terminated boron-doped diamond (BDD) electrodes were used as the working electrode. The DP voltammogram for a solution containing DA and AA obtained using a 4-pentenoic acid-modified BDD (4PA-BDD) electrode showed well-separated oxidation peaks for DA and AA at 0.4 and 0.6 V vs. Ag/AgCl, respectively. In addition, as the DA concentration increased at constant AA concentration, a simultaneous increase in the DA peak current density and decrease in the AA peak current density were observed. The slope of the calibration curve for the [DA] range of 1-10 μM in the presence of AA (500 μM) was seven times larger than that obtained in the absence of AA. Such an enhancement was found to be more efficient at 4PA-BDD than at oxidized-BDD, partly due to simple electrostatic effects and partly due to suppression of the polymerization of DA oxidation products by the terminal carboxyl groups. The enhanced detection method using a carboxyl-terminated BDD electrode should be an effective analytical tool, especially for determining low concentrations of DA in the presence of high concentrations of AA.",

keywords = "Boron-doped diamond, Carboxyl-terminated surface, Differential pulse voltammetry, Dopamine, Electrochemical amplification",

author = "Takeshi Kondo and Yu Niwano and Akira Tamura and Junichi Imai and Kensuke Honda and Yasuaki Einaga and Tryk, {Donald A.} and Akira Fujishima and Takeshi Kawai",

note = "Funding Information: This work was supported by the CLUSTER program of the Ministry of Education, Culture, Sports, Science and Technology, Japan; the Saneyoshi Scholarship Foundation (No. 1725) and the Kurata Memorial Hitachi Science and Technology Foundation (2007).",

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T1 - Enhanced electrochemical response in oxidative differential pulse voltammetry of dopamine in the presence of ascorbic acid at carboxyl-terminated boron-doped diamond electrodes

AU - Kondo, Takeshi

AU - Niwano, Yu

AU - Tamura, Akira

AU - Imai, Junichi

AU - Honda, Kensuke

AU - Einaga, Yasuaki

AU - Tryk, Donald A.

AU - Fujishima, Akira

AU - Kawai, Takeshi

N1 - Funding Information: This work was supported by the CLUSTER program of the Ministry of Education, Culture, Sports, Science and Technology, Japan; the Saneyoshi Scholarship Foundation (No. 1725) and the Kurata Memorial Hitachi Science and Technology Foundation (2007).

PY - 2009/3/1

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N2 - The differential pulse voltammetric (DPV) peak for dopamine (DA) oxidation was found to be highly amplified by the addition of ascorbic acid (AA) when carboxyl-terminated boron-doped diamond (BDD) electrodes were used as the working electrode. The DP voltammogram for a solution containing DA and AA obtained using a 4-pentenoic acid-modified BDD (4PA-BDD) electrode showed well-separated oxidation peaks for DA and AA at 0.4 and 0.6 V vs. Ag/AgCl, respectively. In addition, as the DA concentration increased at constant AA concentration, a simultaneous increase in the DA peak current density and decrease in the AA peak current density were observed. The slope of the calibration curve for the [DA] range of 1-10 μM in the presence of AA (500 μM) was seven times larger than that obtained in the absence of AA. Such an enhancement was found to be more efficient at 4PA-BDD than at oxidized-BDD, partly due to simple electrostatic effects and partly due to suppression of the polymerization of DA oxidation products by the terminal carboxyl groups. The enhanced detection method using a carboxyl-terminated BDD electrode should be an effective analytical tool, especially for determining low concentrations of DA in the presence of high concentrations of AA.

AB - The differential pulse voltammetric (DPV) peak for dopamine (DA) oxidation was found to be highly amplified by the addition of ascorbic acid (AA) when carboxyl-terminated boron-doped diamond (BDD) electrodes were used as the working electrode. The DP voltammogram for a solution containing DA and AA obtained using a 4-pentenoic acid-modified BDD (4PA-BDD) electrode showed well-separated oxidation peaks for DA and AA at 0.4 and 0.6 V vs. Ag/AgCl, respectively. In addition, as the DA concentration increased at constant AA concentration, a simultaneous increase in the DA peak current density and decrease in the AA peak current density were observed. The slope of the calibration curve for the [DA] range of 1-10 μM in the presence of AA (500 μM) was seven times larger than that obtained in the absence of AA. Such an enhancement was found to be more efficient at 4PA-BDD than at oxidized-BDD, partly due to simple electrostatic effects and partly due to suppression of the polymerization of DA oxidation products by the terminal carboxyl groups. The enhanced detection method using a carboxyl-terminated BDD electrode should be an effective analytical tool, especially for determining low concentrations of DA in the presence of high concentrations of AA.

KW - Boron-doped diamond

KW - Carboxyl-terminated surface

KW - Differential pulse voltammetry

KW - Dopamine

KW - Electrochemical amplification

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Enhanced electrochemical response in oxidative differential pulse voltammetry of dopamine in the presence of ascorbic acid at carboxyl-terminated boron-doped diamond electrodes

Abstract

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