Abstract
The differential pulse voltammetric (DPV) peak for dopamine (DA) oxidation was found to be highly amplified by the addition of ascorbic acid (AA) when carboxyl-terminated boron-doped diamond (BDD) electrodes were used as the working electrode. The DP voltammogram for a solution containing DA and AA obtained using a 4-pentenoic acid-modified BDD (4PA-BDD) electrode showed well-separated oxidation peaks for DA and AA at 0.4 and 0.6 V vs. Ag/AgCl, respectively. In addition, as the DA concentration increased at constant AA concentration, a simultaneous increase in the DA peak current density and decrease in the AA peak current density were observed. The slope of the calibration curve for the [DA] range of 1-10 μM in the presence of AA (500 μM) was seven times larger than that obtained in the absence of AA. Such an enhancement was found to be more efficient at 4PA-BDD than at oxidized-BDD, partly due to simple electrostatic effects and partly due to suppression of the polymerization of DA oxidation products by the terminal carboxyl groups. The enhanced detection method using a carboxyl-terminated BDD electrode should be an effective analytical tool, especially for determining low concentrations of DA in the presence of high concentrations of AA.
| Original language | English |
|---|---|
| Pages (from-to) | 2312-2319 |
| Number of pages | 8 |
| Journal | Electrochimica Acta |
| Volume | 54 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 2009 Mar 1 |
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Keywords
- Boron-doped diamond
- Carboxyl-terminated surface
- Differential pulse voltammetry
- Dopamine
- Electrochemical amplification
ASJC Scopus subject areas
- Electrochemistry
- Chemical Engineering(all)
Cite this
Enhanced electrochemical response in oxidative differential pulse voltammetry of dopamine in the presence of ascorbic acid at carboxyl-terminated boron-doped diamond electrodes. / Kondo, Takeshi; Niwano, Yu; Tamura, Akira; Imai, Junichi; Honda, Kensuke; Einaga, Yasuaki; Tryk, Donald A.; Fujishima, Akira; Kawai, Takeshi.
In: Electrochimica Acta, Vol. 54, No. 8, 01.03.2009, p. 2312-2319.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Enhanced electrochemical response in oxidative differential pulse voltammetry of dopamine in the presence of ascorbic acid at carboxyl-terminated boron-doped diamond electrodes
AU - Kondo, Takeshi
AU - Niwano, Yu
AU - Tamura, Akira
AU - Imai, Junichi
AU - Honda, Kensuke
AU - Einaga, Yasuaki
AU - Tryk, Donald A.
AU - Fujishima, Akira
AU - Kawai, Takeshi
PY - 2009/3/1
Y1 - 2009/3/1
N2 - The differential pulse voltammetric (DPV) peak for dopamine (DA) oxidation was found to be highly amplified by the addition of ascorbic acid (AA) when carboxyl-terminated boron-doped diamond (BDD) electrodes were used as the working electrode. The DP voltammogram for a solution containing DA and AA obtained using a 4-pentenoic acid-modified BDD (4PA-BDD) electrode showed well-separated oxidation peaks for DA and AA at 0.4 and 0.6 V vs. Ag/AgCl, respectively. In addition, as the DA concentration increased at constant AA concentration, a simultaneous increase in the DA peak current density and decrease in the AA peak current density were observed. The slope of the calibration curve for the [DA] range of 1-10 μM in the presence of AA (500 μM) was seven times larger than that obtained in the absence of AA. Such an enhancement was found to be more efficient at 4PA-BDD than at oxidized-BDD, partly due to simple electrostatic effects and partly due to suppression of the polymerization of DA oxidation products by the terminal carboxyl groups. The enhanced detection method using a carboxyl-terminated BDD electrode should be an effective analytical tool, especially for determining low concentrations of DA in the presence of high concentrations of AA.
AB - The differential pulse voltammetric (DPV) peak for dopamine (DA) oxidation was found to be highly amplified by the addition of ascorbic acid (AA) when carboxyl-terminated boron-doped diamond (BDD) electrodes were used as the working electrode. The DP voltammogram for a solution containing DA and AA obtained using a 4-pentenoic acid-modified BDD (4PA-BDD) electrode showed well-separated oxidation peaks for DA and AA at 0.4 and 0.6 V vs. Ag/AgCl, respectively. In addition, as the DA concentration increased at constant AA concentration, a simultaneous increase in the DA peak current density and decrease in the AA peak current density were observed. The slope of the calibration curve for the [DA] range of 1-10 μM in the presence of AA (500 μM) was seven times larger than that obtained in the absence of AA. Such an enhancement was found to be more efficient at 4PA-BDD than at oxidized-BDD, partly due to simple electrostatic effects and partly due to suppression of the polymerization of DA oxidation products by the terminal carboxyl groups. The enhanced detection method using a carboxyl-terminated BDD electrode should be an effective analytical tool, especially for determining low concentrations of DA in the presence of high concentrations of AA.
KW - Boron-doped diamond
KW - Carboxyl-terminated surface
KW - Differential pulse voltammetry
KW - Dopamine
KW - Electrochemical amplification
UR - http://www.scopus.com/inward/record.url?scp=59849101794&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=59849101794&partnerID=8YFLogxK
U2 - 10.1016/j.electacta.2008.10.073
DO - 10.1016/j.electacta.2008.10.073
M3 - Article
VL - 54
SP - 2312
EP - 2319
JO - Electrochimica Acta
JF - Electrochimica Acta
SN - 0013-4686
IS - 8
ER -