Enzyme-mediated optical resolution of 2-methyl-3,4-pentadien-1-ol, a chiral building block possessing terminal allenyl group

Tadayoshi Konegawa, Yoshikazu Ohtsuka, Hajime Ikeda, Takeshi Sugai, Hiromichi Ohta

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Both enantiomers (>95% e.e.) of 2-methyl-3,4-pentadien-1-ol, a chiral building block possessing a terminal allenyl group were prepared via the two-stage enzymatic kinetic resolution, i.e., a sequence of lipase-catalyzed acetylation (Pseudomonas cepacia) and hydrolysis (Candida antarctica).

Original languageEnglish
Pages (from-to)1297-1299
Number of pages3
JournalSynlett
Volume1997
Issue number11
DOIs
Publication statusPublished - 1997 Jan 1

ASJC Scopus subject areas

  • Organic Chemistry

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