Eosinophilic pustular folliculitis (Ofuji's disease)

Indomethacin as a first choice of treatment

T. Ota, Y. Hata, Akiko Tanikawa, Masayuki Amagai, M. Tanaka, T. Nishikawa

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Eosinophilic pustular folliculitis (EPF) is characterized by erythematous patches of large follicular papules and pustules involving mainly the face. Although various treatments have been attempted for EPF, including systemic and topical steroid, diaphenylsulphone, colchicine, minocycline as well as UVB phototherapy, there is no consensus on the first choice of treatment. We report a typical case and summarize 25 patients with EPF treated in our hospital between 1978 and 1998. Indomethacin was most frequently used (12/25) and showed clinical improvement in the majority of the cases (11/12). The effect of indomethacin was usually observed within 1-2 weeks after initiation of treatment. Decrease of peripheral blood eosinophils accompanied the clinical improvement. Thus, indomethacin should be considered as a first choice of treatment for EPF.

Original languageEnglish
Pages (from-to)179-181
Number of pages3
JournalClinical and Experimental Dermatology
Volume26
Issue number2
DOIs
Publication statusPublished - 2001

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Indomethacin
Dapsone
Minocycline
Phototherapy
Colchicine
Therapeutics
Eosinophils
Steroids
Eosinophilic pustular folliculitis

ASJC Scopus subject areas

  • Dermatology

Cite this

Eosinophilic pustular folliculitis (Ofuji's disease) : Indomethacin as a first choice of treatment. / Ota, T.; Hata, Y.; Tanikawa, Akiko; Amagai, Masayuki; Tanaka, M.; Nishikawa, T.

In: Clinical and Experimental Dermatology, Vol. 26, No. 2, 2001, p. 179-181.

Research output: Contribution to journalArticle

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