Epidemiological Features of Moyamoya Disease in Japan

Haruhiko Hoshino, Yoshikane Izawa, Norihiro Suzuki

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

To clarify the clinical features of moyamoya disease in Japan, 941 patients with definite moyamoya disease were analyzed from the databases constructed by the Research Committee on Moyamoya Disease, established by the Ministry of Health, Labour and Welfare. Moyamoya disease occurs much more frequently among women than men, with a female-to-male ratio of 1.98. A family history of the disease was observed in 14.9%. The age at onset was characterized by two peaks: one at 5-9 years and another lower peak at around 40 years. Initial clinical features were transient ischemic attack in 46%, infarction in 20%, hemorrhage in 21%, headache in 6%, and epilepsy in 4%. The distribution of the age at onset showed one peak at around 40 years in patients with hemorrhage but two peaks in patients with ischemia.

Original languageEnglish
Pages (from-to)295-298
Number of pages4
JournalNeurologia Medico-Chirurgica
Volume52
Issue number5
Publication statusPublished - 2012

Fingerprint

Moyamoya Disease
Japan
Age of Onset
Hemorrhage
Transient Ischemic Attack
Infarction
Headache
Epilepsy
Ischemia
Databases
Health
Research

Keywords

  • Age at onset
  • Clinical feature
  • Epidemiology
  • Japanese ministry of health
  • Labour and welfare
  • Moyamoya disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Epidemiological Features of Moyamoya Disease in Japan. / Hoshino, Haruhiko; Izawa, Yoshikane; Suzuki, Norihiro.

In: Neurologia Medico-Chirurgica, Vol. 52, No. 5, 2012, p. 295-298.

Research output: Contribution to journalArticle

Hoshino, H, Izawa, Y & Suzuki, N 2012, 'Epidemiological Features of Moyamoya Disease in Japan', Neurologia Medico-Chirurgica, vol. 52, no. 5, pp. 295-298.
Hoshino, Haruhiko ; Izawa, Yoshikane ; Suzuki, Norihiro. / Epidemiological Features of Moyamoya Disease in Japan. In: Neurologia Medico-Chirurgica. 2012 ; Vol. 52, No. 5. pp. 295-298.
@article{de0e87675874492a91a9b9a0244ac38e,
title = "Epidemiological Features of Moyamoya Disease in Japan",
abstract = "To clarify the clinical features of moyamoya disease in Japan, 941 patients with definite moyamoya disease were analyzed from the databases constructed by the Research Committee on Moyamoya Disease, established by the Ministry of Health, Labour and Welfare. Moyamoya disease occurs much more frequently among women than men, with a female-to-male ratio of 1.98. A family history of the disease was observed in 14.9{\%}. The age at onset was characterized by two peaks: one at 5-9 years and another lower peak at around 40 years. Initial clinical features were transient ischemic attack in 46{\%}, infarction in 20{\%}, hemorrhage in 21{\%}, headache in 6{\%}, and epilepsy in 4{\%}. The distribution of the age at onset showed one peak at around 40 years in patients with hemorrhage but two peaks in patients with ischemia.",
keywords = "Age at onset, Clinical feature, Epidemiology, Japanese ministry of health, Labour and welfare, Moyamoya disease",
author = "Haruhiko Hoshino and Yoshikane Izawa and Norihiro Suzuki",
year = "2012",
language = "English",
volume = "52",
pages = "295--298",
journal = "Neurologia Medico-Chirurgica",
issn = "0470-8105",
publisher = "Japan Neurosurgical Society",
number = "5",

}

TY - JOUR

T1 - Epidemiological Features of Moyamoya Disease in Japan

AU - Hoshino, Haruhiko

AU - Izawa, Yoshikane

AU - Suzuki, Norihiro

PY - 2012

Y1 - 2012

N2 - To clarify the clinical features of moyamoya disease in Japan, 941 patients with definite moyamoya disease were analyzed from the databases constructed by the Research Committee on Moyamoya Disease, established by the Ministry of Health, Labour and Welfare. Moyamoya disease occurs much more frequently among women than men, with a female-to-male ratio of 1.98. A family history of the disease was observed in 14.9%. The age at onset was characterized by two peaks: one at 5-9 years and another lower peak at around 40 years. Initial clinical features were transient ischemic attack in 46%, infarction in 20%, hemorrhage in 21%, headache in 6%, and epilepsy in 4%. The distribution of the age at onset showed one peak at around 40 years in patients with hemorrhage but two peaks in patients with ischemia.

AB - To clarify the clinical features of moyamoya disease in Japan, 941 patients with definite moyamoya disease were analyzed from the databases constructed by the Research Committee on Moyamoya Disease, established by the Ministry of Health, Labour and Welfare. Moyamoya disease occurs much more frequently among women than men, with a female-to-male ratio of 1.98. A family history of the disease was observed in 14.9%. The age at onset was characterized by two peaks: one at 5-9 years and another lower peak at around 40 years. Initial clinical features were transient ischemic attack in 46%, infarction in 20%, hemorrhage in 21%, headache in 6%, and epilepsy in 4%. The distribution of the age at onset showed one peak at around 40 years in patients with hemorrhage but two peaks in patients with ischemia.

KW - Age at onset

KW - Clinical feature

KW - Epidemiology

KW - Japanese ministry of health

KW - Labour and welfare

KW - Moyamoya disease

UR - http://www.scopus.com/inward/record.url?scp=84861606629&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84861606629&partnerID=8YFLogxK

M3 - Article

VL - 52

SP - 295

EP - 298

JO - Neurologia Medico-Chirurgica

JF - Neurologia Medico-Chirurgica

SN - 0470-8105

IS - 5

ER -