Epstein-Barr virus-associated T/natural killer-cell lymphomas in the elderly: The first consensus meeting in Kofu 2013

Toshihisa Hamada, Shigeo Nakamura, Young Hyeh Ko, Tadashi Yoshino, Koichi Ohshima, Takamitsu Matsuzawa, Keiko Miura, Toshifumi Takahashi, Hisashi Nomura, Tomomi Hoshino, Daisuke Suzuki, Shinji Shimada, Keiji Iwatsuki

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

From a clinicopathological conference on nine elderly patients with Epstein-Barr virus (EBV)-associated T/natural killer (NK)-cell lymphoma, we have addressed the patients' backgrounds, clinical manifestations, histopathological findings, cytogenesis, complications and prognoses. Among these elderly patients (>65 years old), seven patients had extranodal NK/T-cell lymphoma, nasal type (ENKL) with an NK-cell phenotype, and two patients had EBV + T-cell lymphomas or lymphoproliferative disorders (LPD) with cutaneous lesions mimicking pityriasis lichenoides et varioliformis acuta (PLEVA) or hydroa vacciniforme (HV). No patients had a previous episode of EBV-related symptoms such as infectious mononucleosis, chronic active EBV infection, HV or hypersensitivity to mosquito bites. Elderly patients with ENKL may show the centroblastoid variant. EBV+CD8+CD56 +/- lymphocytes may be responsible for the development of PLEVA or HV-like cutaneous lesions in the elderly.

Original languageEnglish
Pages (from-to)40-42
Number of pages3
JournalJournal of Dermatology
Volume41
Issue number1
DOIs
Publication statusPublished - 2014 Jan 1
Externally publishedYes

Fingerprint

Natural Killer T-Cells
Human Herpesvirus 4
Lymphoma
Hydroa Vacciniforme
Pityriasis Lichenoides
T-Cell Lymphoma
Skin
Infectious Mononucleosis
Epstein-Barr Virus Infections
Lymphoproliferative Disorders
Bites and Stings
Culicidae
Nose
Natural Killer Cells
Hypersensitivity
Lymphocytes
Phenotype

Keywords

  • centroblastoid
  • Epstein-Barr virus
  • hydroa vacciniforme
  • nasal type
  • T/natural killer-cell lymphoma

ASJC Scopus subject areas

  • Dermatology

Cite this

Hamada, T., Nakamura, S., Ko, Y. H., Yoshino, T., Ohshima, K., Matsuzawa, T., ... Iwatsuki, K. (2014). Epstein-Barr virus-associated T/natural killer-cell lymphomas in the elderly: The first consensus meeting in Kofu 2013. Journal of Dermatology, 41(1), 40-42. https://doi.org/10.1111/1346-8138.12373

Epstein-Barr virus-associated T/natural killer-cell lymphomas in the elderly : The first consensus meeting in Kofu 2013. / Hamada, Toshihisa; Nakamura, Shigeo; Ko, Young Hyeh; Yoshino, Tadashi; Ohshima, Koichi; Matsuzawa, Takamitsu; Miura, Keiko; Takahashi, Toshifumi; Nomura, Hisashi; Hoshino, Tomomi; Suzuki, Daisuke; Shimada, Shinji; Iwatsuki, Keiji.

In: Journal of Dermatology, Vol. 41, No. 1, 01.01.2014, p. 40-42.

Research output: Contribution to journalArticle

Hamada, T, Nakamura, S, Ko, YH, Yoshino, T, Ohshima, K, Matsuzawa, T, Miura, K, Takahashi, T, Nomura, H, Hoshino, T, Suzuki, D, Shimada, S & Iwatsuki, K 2014, 'Epstein-Barr virus-associated T/natural killer-cell lymphomas in the elderly: The first consensus meeting in Kofu 2013', Journal of Dermatology, vol. 41, no. 1, pp. 40-42. https://doi.org/10.1111/1346-8138.12373
Hamada, Toshihisa ; Nakamura, Shigeo ; Ko, Young Hyeh ; Yoshino, Tadashi ; Ohshima, Koichi ; Matsuzawa, Takamitsu ; Miura, Keiko ; Takahashi, Toshifumi ; Nomura, Hisashi ; Hoshino, Tomomi ; Suzuki, Daisuke ; Shimada, Shinji ; Iwatsuki, Keiji. / Epstein-Barr virus-associated T/natural killer-cell lymphomas in the elderly : The first consensus meeting in Kofu 2013. In: Journal of Dermatology. 2014 ; Vol. 41, No. 1. pp. 40-42.
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