TY - JOUR
T1 - Erythema exsudativum multiforme induced by granulocyte colony-stimulating factor in an allogeneic peripheral blood stem cell donor
AU - Mori, T.
AU - Sato, N.
AU - Watanabe, R.
AU - Okamoto, S.
AU - Ikeda, Y.
PY - 2000
Y1 - 2000
N2 - We describe a healthy peripheral blood stem cell (PBSC) donor who developed a cutaneous reaction, erythema exsudativum multiforme, during the administration of granulocyte colony-stimulating factor (G-CSF) for mobilization. The cutaneous lesions were located on his hips, apart from the site of G-CSF injection. Treatment with topical corticosteroid was commenced, and the lesions resolved completely within a week. Adverse cutaneous reactions induced by G-CSF have been reported infrequently in healthy donors. Further documentation of cases and their full evaluation will be of great importance for both physicians and PBSC donor.
AB - We describe a healthy peripheral blood stem cell (PBSC) donor who developed a cutaneous reaction, erythema exsudativum multiforme, during the administration of granulocyte colony-stimulating factor (G-CSF) for mobilization. The cutaneous lesions were located on his hips, apart from the site of G-CSF injection. Treatment with topical corticosteroid was commenced, and the lesions resolved completely within a week. Adverse cutaneous reactions induced by G-CSF have been reported infrequently in healthy donors. Further documentation of cases and their full evaluation will be of great importance for both physicians and PBSC donor.
KW - Erythema exsudativum multiforme
KW - Granulocyte colony-stimulating factor
KW - Peripheral blood stem cell donor
KW - Side-effect
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U2 - 10.1038/sj.bmt.1702501
DO - 10.1038/sj.bmt.1702501
M3 - Article
C2 - 10918440
AN - SCOPUS:0033915467
VL - 26
SP - 239
EP - 240
JO - Bone Marrow Transplantation
JF - Bone Marrow Transplantation
SN - 0268-3369
IS - 2
ER -