Esophageal adenocarcinoma with white opaque substance observed by magnifying endoscopy with narrow band imaging

Shunsuke Yoshii, Motohiko Kato, Keiichiro Honma, Tetsuji Fujinaga, Yoshiki Tsujii, Akira Maekawa, Takuya Inoue, Yoshito Hayashi, Tomofumi Akasaka, Shinichiro Shinzaki, Tsutomu Nishida, Hideki Iijima, Masahiko Tsujii, Eiichi Morii, Tetsuo Takehara

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

White opaque substance (WOS) is observed in the gastric neoplasia of 0-IIa type using magnifying endoscopy with narrow band imaging (NBI-ME). Colonic and duodenal neoplasms with WOS have also been reported. Immunohistochemical examination with adipophilin reveals WOS in gastric neoplasms as lipid droplets, and WOS is specific for neoplasm with intestinal or gastrointestinal phenotype. We herein report a case of adenocarcinoma of the esophagogastric junction with WOS. A male patient in his sixties was found by esophagogastroduodenoscopy to have an esophageal elevated lesion. NBI-ME showed whitish deposits that looked similar to WOS in gastric neoplasms. The patient underwent endoscopic submucosal dissection and the lesion was resected in a single piece. This tumor had diffuse positivity for adipophilin and gastrointestinal phenotype.

Original languageEnglish
Pages (from-to)392-396
Number of pages5
JournalDigestive Endoscopy
Volume27
Issue number3
DOIs
Publication statusPublished - 2015 Mar 1
Externally publishedYes

Keywords

  • adenocarcinoma
  • esophageal cancer
  • magnifying endoscopy
  • narrow band imaging (NBI)
  • white opaque substance (WOS)

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

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