Establishment and characterization of the RMG-V cell line from human ovarian clear cell adenocarcinoma.

Daisuke Aoki, Nao Suzuki, Nobuyuki Susumu, Tomomi Noda, Atsushi Suzuki, Yutaka Tamada, Atsushi Higashiguchi, Shinji Oie, Shiro Nozawa

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

A cell line, designated as RMG-V, was established from a patient with clear cell adenocarcinoma of the ovary. The cell line has grown without interruption and has been propagated continuously by serial passaging (more than 36 times) over 5 years. The cells are spindle-shaped, display neoplastic and pleomorphic features, and grow in a jigsaw puzzle-like arrangement while forming monolayers without contact inhibition. These cells proliferate rapidly, and the population doubling time is about 15.5 hours. The number of chromosomes ranges between 77 and 85, with a modal number of 83.

Original languageEnglish
Pages (from-to)143-146
Number of pages4
JournalHuman cell : official journal of Human Cell Research Society
Volume18
Issue number3
Publication statusPublished - 2005 Sep

ASJC Scopus subject areas

  • Cell Biology
  • Cancer Research

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