Establishment of the structure of gymnemagenin by x-ray analysis and the structure of deacylgymnemic acid

Yoshisuke Tsuda, Fumiyuki Kiuchi, Hong Min Liu

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The structure of gymnemagenin, the sapogenin of antisweet principle of Gymnema syrvestre, was firmly established as 3β,16β,21β,22α,23,28-hexahydroxy-olean-12-ene by the X-ray analysis of the 3β,23;21β,2???α-di-O-isopropylidene derivative. On the basis of this result, the structure of deacylgymnemic acid was elucidated as the 3-O-β-glucuronide by comparisons of the 13C-NMR spectra.

Original languageEnglish
Pages (from-to)361-362
Number of pages2
JournalTetrahedron Letters
Volume30
Issue number3
DOIs
Publication statusPublished - 1989
Externally publishedYes

Fingerprint

Gymnema
Sapogenins
Glucuronides
X ray analysis
Nuclear magnetic resonance
X-Rays
Derivatives
X rays
deacylgymnemic acid
gymnemagenin
propylene
Carbon-13 Magnetic Resonance Spectroscopy

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Establishment of the structure of gymnemagenin by x-ray analysis and the structure of deacylgymnemic acid. / Tsuda, Yoshisuke; Kiuchi, Fumiyuki; Liu, Hong Min.

In: Tetrahedron Letters, Vol. 30, No. 3, 1989, p. 361-362.

Research output: Contribution to journalArticle

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